TY - BOOK ID - 134169292 TI - Enzyme Inhibitor from Marine Organisms PY - 2020 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Research & information: general KW - sponge Monanchora pulchra KW - pentacyclic guanidine alkaloids KW - GH36 α-galactosidase KW - GH109 α-N-acetylgalactosaminidase KW - slow-binding irreversible inhibitor KW - monanchomycalin B KW - monanhocidin A KW - normonanhocidin A KW - Alzheimer′s disease KW - BACE1 KW - acetylcholinesterase KW - in silico docking KW - phlorotannins KW - Ulva intestinalis KW - ACE inhibitory peptide KW - optimization KW - purification KW - structural identification KW - molecular docking KW - secondary metabolites KW - Mycosphaerella sp. KW - asperchalasine KW - α-glucosidase KW - kinase inhibitors KW - drug development KW - marine natural products KW - inhibitor KW - macroalgae KW - marine fish KW - protease KW - Ulva ohnoi KW - functional annotation KW - structure–function relation KW - natural products KW - bioactives KW - enzyme inhibition KW - inactivation KW - marine bacteria KW - marine fungi KW - marine sponges UR - https://www.unicat.be/uniCat?func=search&query=sysid:134169292 AB - Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects. ER -