TY - BOOK ID - 133465683 TI - Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer PY - 2022 PB - Basel MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Public health & preventive medicine KW - nucleus accumbens-associated protein 1 (NAC1) KW - BEN (BANP, E5R and NAC1) domain KW - sequence-specific DNA-binding protein KW - solution NMR structure KW - isothermal titration calorimetry (ITC) KW - human cytomegalovirus KW - ovarian cancer KW - cancer progression KW - inflammation KW - immunosuppression KW - endometrial carcinoma KW - immune micro-environment KW - immune checkpoints inhibitors KW - microsatellite instability KW - mismatch repair deficiency KW - platelet-activating factor acetylhydrolase (PAF-AH KW - PLA2G7) KW - BRCA1 mutant ovarian cancer KW - Wnt signaling KW - pGSK3β KW - β-catenin KW - prognosis KW - vulvar melanoma KW - vaginal melanoma KW - targeted therapy KW - gynecological cancer KW - melanoma treatment KW - gene ontology KW - epithelial ovarian cancers KW - borderline ovarian tumors KW - differentially expressed genes KW - aryl hydrocarbon receptor KW - epithelial–mesenchymal transition KW - integrative analysis KW - testin KW - p16 protein KW - cervical cancer KW - cervical neoplasia KW - immunohistochemistry KW - chimeric antigen receptor KW - CD44 KW - adoptive immunotherapy KW - NK cells KW - epithelial ovarian cancer KW - DNA damage response KW - somatic mutation KW - clear cell carcinoma KW - endometrioid endometrial cancer KW - DNA mismatch repair (MMR) KW - MMR deficient (dMMR) KW - long-term survival KW - exosome KW - miRNA KW - biomarkers KW - liquid biopsy KW - interventional radiotherapy KW - vaginal-cuff brachytherapy KW - HDR brachytherapy KW - in vivo dosimetry KW - endometrial cancer KW - biological planning KW - drug repurposing KW - non-coding RNAs KW - nanocarriers KW - anti-angiogenic therapy KW - n/a KW - epithelial-mesenchymal transition UR - https://www.unicat.be/uniCat?func=search&query=sysid:133465683 AB - This book—entitled “Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer”—was edited as a Special Issue of Biomedicines, focusing on basic research such as genomics, epigenomics, and proteomics, as well as clinical research in the field of gynecologic oncology. The number of patients with gynecological cancer has been increasing worldwide due to its high lethality and lack of early detection tools and effective therapeutic interventions. In this regard, basic research on its pathophysiology and novel molecular targeting intervention is required to improve the prognosis of gynecologic cancer. This book contains 13 papers, including 8 original research papers and 5 reviews focusing on the basic research of gynecologic oncology. The reader can learn about state-of-the-art research and obtain extensive knowledge of the current advances in the field of gynecologic oncology. It is my hope that this book contributes towards the progress of gynecologic oncology. ER -