TY - BOOK ID - 133355498 TI - Oxidative Stress in Diabetic Retinopathy PY - 2021 PB - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Medicine KW - eicosanoids KW - oxidative stress KW - diabetic retinopathy KW - cyclooxygenase KW - lipoxygenase KW - Cytochrome P450 KW - HDAC6 KW - tubastatin A KW - retinal endothelial cells KW - retinal endothelial cell senescence KW - db/db mice KW - Cinnamomi Ramulus KW - Paeoniae Radix KW - CPA4-1 KW - blood-retinal barrier KW - occludin KW - human retina KW - epiretinal membrane KW - internal limiting membrane KW - vitreoretinal surgery KW - macular hole KW - proliferative diabetic retinopathy KW - antioxidants KW - diabetes mellitus KW - free radicals KW - high-mobility group box 1 (HMGB1) KW - inflammatory pathways KW - novel therapies KW - diabetic retinopathy (DR) KW - inflammation KW - angiogenesis KW - extracellular vesicles KW - miRNA KW - biomarkers KW - apoptosis KW - fenofibrate KW - thioredoxin KW - hyperglycemia KW - astaxanthin KW - carotenoid KW - reactive oxygen species KW - photoreceptor cells KW - PI3K KW - Nrf2 KW - eicosapentaenoic acid (EPA) KW - docosahexaenoic acid (DHA) KW - retinal pigment epithelium KW - antioxidant KW - ascorbic acid KW - retinal disease KW - vitamin D KW - GLP-1 KW - superoxide dismutase KW - biomarkers of diabetic retinopathy KW - metabolic memory KW - tear film KW - aqueous humor KW - vitreous humor KW - mitochondria KW - redox KW - photoreceptor KW - glycation KW - aging KW - glyoxalase KW - n/a UR - https://www.unicat.be/uniCat?func=search&query=sysid:133355498 AB - The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue. ER -