TY - GEN digital ID - 131709319 TI - Inflammation and Retinal Disease: Complement Biology and Pathology AU - Lambris, John D. AU - Adamis, Anthony P. PY - 2010 SN - 9781441956354 9781441956347 9781461426486 9781441956361 PB - New York, NY Springer DB - UniCat KW - Ophthalmology KW - oftalmologie UR - https://www.unicat.be/uniCat?func=search&query=sysid:131709319 AB - Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical candidates covering a wide area of potential treatment applications are in the pipelines of both industrial and academic groups. This indicates an increasing interest in complement as a therapeutic target. In view of these exciting discoveries, scientists from around the world convened at the 1st Aegean Conferences Conference on Inflammation and Retinal Disease: Complement Biology and Pathology (June 10-17, 2007) in Crete, Greece, to discuss recent advances in this rapidly-evolving field. This volume represents a collection of topics on the functions of complement in eye diseases, pathophysiology, protein structures, and complement therapeutics discussed during the conference. ER -