TY - BOOK ID - 129680930 TI - Immune Maturation and Modulation in Childhood Allergies : Aspects of Epigenetic, Mucosal and Systemic Immune Mediators in Allergy Development and Prevention. PY - 2020 SN - 9179297870 PB - Linköping : Linkopings Universitet, DB - UniCat KW - Allergy in children. KW - Immunology. UR - https://www.unicat.be/uniCat?func=search&query=sysid:129680930 AB - This doctoral dissertation by Johanna Huoman explores immune maturation and modulation in childhood allergies, focusing on epigenetic, mucosal, and systemic immune mediators. The research investigates how environmental and microbial exposures affect the development of allergies and the immune system's balance between Th2, Th1, and Treg responses. The study includes analysis of chemokine levels and their association with allergy development, as well as the impact of perinatal treatments with Lactobacillus reuteri and omega-3 fatty acids on DNA methylation in immune cells. The work aims to understand the mechanisms behind allergy prevention and immune modulation in children with a high risk of developing allergic diseases. The intended audience includes researchers and professionals in medical and health sciences, particularly those specializing in immunology and allergy. ER -