TY - BOOK ID - 129522651 TI - Biomarkers and Mediators in Systemic Lupus erythematosus : IFNa Versus the CRP Response, and Evaluation of suPAR and anti-dsDNA Antibody Assays. PY - 2014 SN - 9175193930 9789175193939 PB - Linköping : Linköping University Electronic Press, DB - UniCat KW - Systemic lupus erythematosus. KW - Biochemical markers. UR - https://www.unicat.be/uniCat?func=search&query=sysid:129522651 AB - This dissertation by Helena Enocsson explores the role of biomarkers and mediators in Systemic Lupus Erythematosus (SLE), a complex autoimmune disease that can affect multiple organ systems. The research focuses on Interferon alpha (IFNα) and its potential to inhibit C-reactive protein (CRP) production, impacting the ability to monitor inflammation in SLE. It evaluates the efficacy of various anti-double stranded DNA (anti-dsDNA) antibody assays for SLE diagnosis and monitoring. The study also investigates the association of soluble urokinase plasminogen activator receptor (suPAR) with organ damage rather than disease activity. Through clinical and biological analysis, the dissertation aims to enhance understanding of SLE biomarkers to improve patient management and disease knowledge. ER -