TY - BOOK ID - 119430776 TI - Molecular Mechanisms of Neurotransmitter Release PY - 2023 SN - 3031342291 3031342283 PB - Cham : Springer International Publishing : Imprint: Springer, DB - UniCat KW - Neurosciences. KW - Cytology. KW - Zoology. KW - Neurology. KW - Neuroscience. KW - Cell Biology. KW - Medicine KW - Nervous system KW - Neuropsychiatry KW - Biology KW - Natural history KW - Animals KW - Cell biology KW - Cellular biology KW - Cells KW - Neural sciences KW - Neurological sciences KW - Neuroscience KW - Medical sciences KW - Diseases UR - https://www.unicat.be/uniCat?func=search&query=sysid:119430776 AB - Neurons communicate with each other by releasing neurotransmitters. This book provides comprehensive coverage of the molecular mechanisms involved in neurotransmitter release. The topics covered in the book range from the architecture and cytomatrix proteins of presynaptic sites, to the modes of synaptic vesicle exocytosis (full-collapse and kiss-and-run), and from the key molecules mediating synaptic vesicle fusion (SNAREs) to those that closely interact with them (UNC-13/Munc13, UNC-18/Munc18, tomosyn, and complexins). The book also delves into the calcium sensors of synaptic vesicle fusion (synaptotagmins and Doc2s), the sources of calcium that trigger synaptic exocytosis (voltage-gated calcium channels and ryanodine receptors), and the regulation of neurotransmitter release by potassium channels, cell adhesion molecules, lipids, aryl hydrocarbon receptor-interacting protein (AIP), presenilins, and calstabins. To aid in understanding and illustrate key concepts, the book includes sufficient background information and a wealth of illustrations and diagrams. The new edition includes major updates to previous chapters, as well as several new chapters that reflect the recent advances in the field. Comprehensive and cutting-edge, Molecular Mechanisms of Neurotransmitter Release, 2nd edition, is a valuable learning resource for neuroscience students and a solid reference for neuroscientists. ER -