TY - BOOK ID - 113574240 TI - Marine Glycomics AU - Fujii, Yuki AU - Gerdol, Marco AU - Ozeki, Yasuhiro PY - 2022 SN - 3036558225 3036558217 PB - Basel MDPI - Multidisciplinary Digital Publishing Institute DB - UniCat KW - Research & information: general KW - Biology, life sciences KW - Acropora tenuis KW - coral KW - chemoattraction KW - lectin KW - white-spotted charr lectin KW - oncolytic vaccinia virus KW - interferon KW - antiviral response KW - Chlorella vulgaris KW - Dunaliella salina KW - Arthrospira platensis KW - growth rate KW - accumulation of carbohydrates KW - biohydrogen KW - antibacterial activity KW - anticancer activity KW - antifungal activity KW - Aplysia kurodai KW - apoptosis KW - Ehrlich ascites carcinoma KW - sulfated fucose-rich polysaccharides KW - sulfated fucan KW - fucosylated chondroitin sulfate KW - fucoidan KW - oral administration KW - anticoagulant activity KW - fucosylated glycosaminoglycan KW - anticoagulant KW - platelet aggregation KW - contact activation KW - hypotension KW - pulmonary embolism KW - sulfated polysaccharides KW - marine hydrobionts KW - antiparasitic activity KW - protozoa KW - malaria KW - leishmaniasis KW - trypanosomiasis KW - schistosomiasis KW - cryptosporidiosis KW - trichomoniasis KW - bivalve mollusk KW - C1q domain-containing KW - lectin-like KW - pattern recognition receptor KW - polysaccharides KW - interstitial compartment KW - marine worms KW - sipunculids KW - bioactive properties KW - peptides KW - rotifera KW - pattern recognition receptors KW - microbe-associated molecular patterns KW - innate immunity KW - C-type lectins KW - C1q domain-containing proteins KW - galectins KW - bacterial exopolysaccharides KW - bioflocculanting activity KW - microalgae growth-promoting bacterium KW - harmful algal bloom-forming dinoflagellate KW - Alexandrium catenella KW - Mameliella alba KW - n/a UR - https://www.unicat.be/uniCat?func=search&query=sysid:113574240 AB - Marine creatures are rich sources of glycoconjugate-containing glycans and have diversified structures. The advance of genomics has provided a valuable clue for their production and developments. This information will encourage breeding and engineering functional polysaccharides with slime ingredients in algae. These glycans will have the potential for applications to antioxidant, anticancer, and antimicrobial drugs in addition to health supplements and cosmetics. The combination of both biochemical and transcriptome approaches of marine creatures will lead to the opportunity to discover new activities of proteins such as glycan-relating enzymes and lectins. These proteins will also be used for experimental and medical purposes, such as diagnostics and trial studies. The topic of marine glycomics is also focusing on understanding the physiological properties of marine creatures, such as body defense against pathogens and cancers. In the competitions for natural selection, living creatures have evolved both their glycans and their recognition. They have primitive systems of immunity, and few of their mechanisms are closely related to glycans. If we are able to describe the accumulation of data of glycans of creatures living in the seashore and the oceans, we may be able to anticipate a time when we can talk about the ecosystem with glycans. That knowledge will be useful for the development of drugs that cure our diseases and for an understanding of living systems in addition to the preservation of living environments. ER -