TY - BOOK ID - 113162033 TI - From Pathophysiology to Treatment of Huntington's Disease PY - 2022 SN - 1803554274 PB - London : IntechOpen, DB - UniCat KW - Huntington's disease KW - Pathophysiology. KW - Chronic progressive chorea KW - Chronic progressive hereditary chorea KW - Degenerative chorea KW - HC (Disease) KW - HD (Disease) KW - Hereditary chorea KW - Huntington chorea KW - Huntington chronic progressive hereditary chorea KW - Huntington disease KW - Huntington's chorea KW - Lund-Huntington chorea KW - Microcellular striatal syndrome KW - Progressive hereditary chorea, Chronic KW - Chorea KW - Dementia KW - Genetic disorders KW - Nervous system KW - Degeneration UR - https://www.unicat.be/uniCat?func=search&query=sysid:113162033 AB - Huntington's Disease (HD) is a progressive neurodegenerative disease leading to a variety of neurological and psychiatric symptoms such as chorea, parkinsonism, oculomotor symptoms, cognitive decline, depression, suicidal ideation, and psychosis. Currently, only symptomatic treatment is available. In recent years, there has been a growing number of publications regarding pathophysiology, disease biomarkers, and possible avenues for causal therapy of HD. This book presents an overview of the most important research updates in the pathophysiology and treatment of HD, with particular reference to advances in HD neuropathology, neuroimaging, and biomarkers of HD. We also summarize possible new therapeutic targets, including cannabis-based medicine, cellular, and cell-free therapeutics. Importantly, researchers from different regions of the world have contributed to this volume as we wanted to create a balanced, inclusive, and interdisciplinary review of the topics. We hope that with this book readers will be offered a compact summary of up-to-date trends in HD research which, ultimately, will enable better diagnosis and treatment for HD patients. ER -