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Adaptations to maternal physiology are required for a successful pregnancy outcome. These changes are primarily orchestrated by the mother’s brain and involve multiple neuroendocrine systems. For this book, the editors have gathered internationally recognized experts who have contributed to the major advances in our understanding of different aspects of the neuroendocrine regulation of mammalian pregnancy and lactation. The book begins with a discussion of how pregnancy is recognized and maintained and the role of the placental hormones in supporting key adaptations required for a successful pregnancy. The next few chapters focus on the neuroendocrine adaptations that occur during pregnancy in some key regulatory processes to ensure a sufficient supply of energy and nutrients, protect the fetus from potentially harmful maternal stress hormones, and prepare mammals for birth, milk production, lactation and motherhood. Finally, our current understanding of how the significant peripartum hormonal changes contribute to the mother’s cognitive function and mood is examined. This book provides a broad overview of the finely orchestrated neuroendocrine adaptations that occur in pregnancy and lactation and discusses how such changes contribute to maximizing the likelihood of a positive outcome for mother and infant. Importantly the evidence for involvement of neuroendocrine dysregulation in some pregnancy-related complications, such as preterm birth and perinatal mood disorders is also highlighted. In addition to addressing fundamental mechanisms in the regulation of mammalian pregnancy and lactation, the book includes the most recent advances in the field made possible by utilizing the latest innovative research technologies. Moreover, it provides opinions on optimal experimental approaches, relates findings from experimental animal models with those from humans, and outlines the direction and opportunities for future research in this arena. It is an essential resource for undergraduate students, postgraduate students, and early career researchers embarking upon their journey in the fields of neuroendocrinology, endocrinology, reproductive biology or behavioural neuroscience. It also provides a valuable synopsis for established neuroendocrine researchers and educators, especially those whose interest transcends the nexus between neuroendocrinology and reproductive biology. This is the 15th volume in the International Neuroendocrine Federation (INF) “Masterclass in Neuroendocrinology” series, which aims to illustrate the highest standards and to encourage the use of the latest technologies in basic research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Neuroendocrinology. --- Neurosciences. --- Endocrinology. --- Neurophysiology. --- Endocrine glands. --- Neuroscience. --- Endocrine System.

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"With an emphasis on the "hows and whys" of contemporary surgery, Operative Techniques in Breast, Endocrine, and Oncologic Surgery, Second Edition, features concise, bulleted text, full-color illustrations, and intraoperative photographs to clarify exactly what to look for and how to proceed. Drawn from the larger Operative Techniques in Surgery, Second Edition, this concise, stand-alone surgical atlas, overseen by editor-in-chief Mary T. Hawn and meticulously edited by Dr. Michael S. Sabel, focuses on the steps of each technique, rapidly directing you to the information you need to choose the right approach for each patient, perform it successfully, and achieve the best possible results. Provides comprehensive, step-by-step guidance on breast surgery and reconstruction; cutaneous oncology; and endocrine surgery Covers open as well as laparoscopic, endoscopic, robotic, and video-assisted procedures in breast, endocrine, and oncologic surgery Features new videos, personally selected by contributing authors and editors, that accompany numerous chapters throughout the book Contains extensive updates throughout, including new coverage of the American Board of Surgery's SCORE Curricula for General Surgery and for Complex General Surgical Oncology Follows the same format for each procedure: differential diagnosis, patient history and physical findings, imaging and other diagnostic studies, surgical management, techniques, pearls and pitfalls, postoperative care, outcomes, and complications Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. "--

Breast Neoplasms --- Mammaplasty --- Endocrine System Diseases --- Endocrine Surgical Procedures --- Neoplasms --- surgery --- methods --- surgery --- methods --- surgery

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Steroid Hormone Receptors in Endocrine Physiology and Diseases covers the role of steroid hormones in human physiology and receptor activity in the pathophysiology of disease. The book discusses how these receptors can be used as therapeutic targets for the treatment of conditions from cancer to aging, offering immediate applications of biochemical principles into clinical applications such as diagnosis and treatment. This book is a valuable reference for graduate and postdoctoral scientists but is also ideal for medical students interested in the functional role of various steroid hormone receptors in a wide variety of endocrine related diseases.

Steroid hormones --- Genetic regulation. --- Receptors. --- Receptors, Steroid --- Endocrine glands --- Diseases --- Treatment.

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A l'échelle de la planète, on recense plus de 100 millions de substances chimiques différentes. Si le début du XXIe siècle a vu naître de nombreux progrès règlementaires basés sur la maîtrise des risques liés à l'usage des substances les plus préoccupantes (cancérogènes, persistantes dans l'environnement), il n'en reste pas moins que le niveau d'information acquis sur les substances chimiques en général ne couvre qu'une toute petite partie d'entre elles. En effet, l'usage des produits du quotidien, les activités et les comportements humains nous exposent à toutes ces substances de manière continuelle. Ces expositions, cumulées à d'autres facteurs de risques (alcool, tabac, sédentarité, etc.), participent à l'accroissement des maladies chroniques actuelles (cancers, obésité, maladies cardiovasculaires, diabète...). Cet ouvrage est conçu pour permettre de comprendre les enjeux liés aux substances chimiques, en particulier les perturbateurs endocriniens, molécules qui agissent dans le corps en altérant le système hormonal, et qui font l'objet d'un cadrage règlementaire récent au vu du niveau de préoccupation qu'ils suscitent pour la santé et pour l'environnement. Structuré en 19 fiches, il propose des outils pratiques permettant de repérer ces substances chimiques dans le quotidien, d'analyser les situations les plus à risque, et d'agir en matière de prévention pour la réduction des expositions de la population. L'ouvrage s'adresse spécifiquement aux professionnels de santé qui dans leur pratique quotidienne sont amenés à conseiller citoyens et patients sur cette thématique pouvant apparaître comme anxiogène.

Endocrine disrupting chemicals --- Endocrine disrupting chemicals --- Pollutants --- Perturbateurs endocriniens --- Perturbateurs endocriniens --- Perturbateurs endocriniens. --- Exposition aux perturbateurs endocriniens --- Perturbateurs endocriniens --- Perturbateurs endocriniens --- Government policy --- Prevention. --- Risques pour la santé. --- Politique gouvernementale --- Prévention. --- Risques pour la santé --- Politique publique