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Ghrelin. --- Gastrointestinal hormones. --- Endocrinological gastroenterology --- Gut hormones --- Regulatory gut peptides --- RGP (Hormones) --- Hormones --- Motilin-related peptide --- Gastrointestinal hormones --- Peptide hormones
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This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The volume covers ghrelin, and has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays and inhibition, and thermogenic characterization of ghrelin receptor null mice. Contains quality chapters authored by leaders in the field Has chapters on such topics as orphan gpcrs and methods for identifying their ligands, ghrelin o-acyltransferase assays an
Ghrelin -- Physiological effect. --- Ghrelin. --- Growth hormone. --- Peptide Hormones --- Investigative Techniques --- Peptides --- Hormones --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Amino Acids, Peptides, and Proteins --- Hormones, Hormone Substitutes, and Hormone Antagonists --- Chemicals and Drugs --- Chemistry Techniques, Analytical --- Ghrelin --- Chemistry Techniques, Analytical. --- Enzymes. --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biocatalysts --- Ferments --- Soluble ferments --- Motilin-related peptide --- Composition --- Biology --- Chemistry --- Medical sciences --- Catalysts --- Proteins --- Enzymology --- Gastrointestinal hormones --- Peptide hormones
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Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
Nutrition Therapy. --- Palliative treatment. --- Terminal care. --- Ghrelin --- Metabolic Phenomena --- Peptide Hormones --- Biological Science Disciplines --- Hormones --- Peptides --- Phenomena and Processes --- Natural Science Disciplines --- Disciplines and Occupations --- Amino Acids, Peptides, and Proteins --- Hormones, Hormone Substitutes, and Hormone Antagonists --- Chemicals and Drugs --- Physiology --- Metabolism --- Medicine --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Clinical Endocrinology --- Physiological aspects --- Ghrelin. --- Motilin-related peptide --- Medicine. --- Immunology. --- Neurosciences. --- Nutrition. --- Endocrinology. --- Geriatrics. --- Medicine & Public Health. --- Geriatrics/Gerontology. --- Gastrointestinal hormones --- Peptide hormones --- Alimentation --- Food --- Nutrition --- Health --- Diet --- Dietetics --- Digestion --- Food habits --- Malnutrition --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Immunobiology --- Life sciences --- Serology --- Gerontology --- Older people --- Internal medicine --- Health aspects --- Diseases --- Health and hygiene --- Endocrinology . --- Nutrition .
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