Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Drug carriers --- Drug targeting --- Liposomes --- Liposomes --- pharmacology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of ""healthy genes"" into patients' cells. The problem, however, was that viral vectors proved unnecessarily harmful to humans: subjects experienced inflammatory activity and negative immunological responses to the genes. Viral vectors were also unable to meet the needs of the pharmaceutical community: they were not reproducible in large-scale proportions in cost-effective ways.

DNA-ligand interactions. --- Drug targeting. --- Gene therapy. --- Gene therapy. Genetic vectors. DNA-ligand interactions. Liposomes. Drug targeting. --- Genetic transformation. --- Genetic vectors. --- Liposomes. --- Recombination, Genetic --- Genetic Structures --- Genetic Techniques --- Investigative Techniques --- Genetic Phenomena --- Genetic Processes --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Genetic Vectors --- Gene Transfer Techniques --- Transformation, Genetic --- Medicine --- Health & Biological Sciences --- Pathology --- Gene transfer --- Transformation (Genetics) --- Drugs --- Site-specific drug delivery --- Targeting of drugs --- Phospholipid vesicles --- Binding, DNA-ligand --- DNA-ligand binding --- Interactions, DNA-ligand --- Therapy, Gene --- Cloning vectors --- Expression vectors (Genetics) --- rDNA vectors --- Recombinant DNA vectors --- Vectors, Genetic --- Targeting --- Genetic recombination --- Microbial genetics --- Nucleic acids --- Transfection --- Target organs (Anatomy) --- Bilayer lipid membranes --- Cytoplasm --- Phospholipids --- Ligand binding (Biochemistry) --- Genetic engineering --- Therapeutics --- Gene expression --- Molecular cloning --- Recombinant DNA --- Dosage forms