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Bacterial diseases --- Drug resistance in microorganisms. --- Prevention.

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"Antimicrobial resistance (AMR) is a biological mechanism whereby a micro-organism evolves over time to develop the ability to become resistant to antimicrobial therapies such as antibiotics. The drivers of and potential solutions to AMR are complex, often spanning multiple sectors. The internationally recognised response to AMR advocates for a 'One Health' approach, which requires policies to be developed and implemented across human, animal, and environmental health. To date, misaligned economic incentives have slowed the development of novel antimicrobials and limited efforts to reduce antimicrobial usage. However, the research which underpins the variety of policy options to tackle AMR is rapidly evolving across multiple disciplines such as human medicine, veterinary medicine, agricultural sciences, epidemiology, economics, sociology and psychology. By bringing together in one place the latest evidence and analysing the different facets of the complex problem of tackling AMR, this book offers an accessible summary for policy-makers, academics and students on the big questions around AMR policy"--

Drug resistance in microorganisms --- Drug resistance in microorganisms --- Drug development --- Drug development --- Economic aspects. --- Government policy. --- Economic aspects. --- Government policy.

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Staphylococcus aureus infections. --- Methicillin resistance. --- Drug resistance in microorganisms --- Staphylococcal infections

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In June 1941 a pair of British scientists boarded a plane for America with World War II raging all around them. They carried a precious commodity--penicillin--and the knowledge that it would change history. Once the U.S. government had been debriefed, the Office of Science Research and Development, in conjunction with British counterparts, assumed control, and penicillin became a top-secret matter of national security, second in importance only to the atomic bomb. In Cold War Resistance Marc Landas uncovers the dark history behind the discovery, production, and distribution of penicillin and other antibiotics. In 1949 the United States embargoed any material deemed of "strategic importance," including antibiotics, from going to Communist countries, effectively shutting off the Soviet Union from a modern medical miracle. The Soviets responded by creating satellite antibiotic factories in Warsaw Pact countries that produced subpar antibiotics, which soon led to antibiotic resistance. Today, the number of effective antibiotics available is dwindling, and the state of antibiotic resistance is worsening. The Cold War played a critical role in fostering this resistance, as Landas argues in this pathbreaking history of the international struggle over antibiotics.

Cold War --- Antibiotics industry --- Antibiotics --- Drug resistance in microorganisms. --- Biological warfare. --- History. --- Biological warfare --- History

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Antibiotics: Therapeutic Spectrum and Limitations provides up-to-date information on managing microbial infections, the development and types of antibiotics, the rationale for utilizing antibiotics, toxicity considerations, and the control of antibiotic resistance in one single resource. This book also aims to provide comprehensive insights and current trends on antibiotic therapies to treat microbial infections, their mechanisms of action, and the role of modern drug delivery in improving their efficacy. Written by leading experts from around the globe, the chapters in the book covers important aspects of microbial infections including hospital acquired infections and community acquired infections and adult sepsis, examines the various types of antibiotics with different mechanisms and therapeutic uses, the global challenge of antibiotic resistance, and clinical trials, regulatory considerations, and market overview of antibiotics. Furthermore, the chapters include updated literature reviews of the relevant key topics, high-quality illustrations, chemical structures, flowcharts, and well-organized tables, all of which enable better understanding by the readers.

Antibiotics --- Antibiotics. --- Communicable diseases. --- Drug resistance in microorganisms. --- Anti-Bacterial Agents --- Communicable Diseases --- Drug Resistance, Microbial --- Analysis. --- therapeutic use