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Book
Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.


Periodical
JAC-Antimicrobial Resistance

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Book
Nanotechnology in Animal Science
Authors: ---
ISBN: 3036559469 3036559450 Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Recently, a revolution in nanotechnology has pervaded all fields related to animal science. This book collection focuses on the potential applications of nanotechnology in the field of animal science, particularly livestock production and medication. The studies/reviews published in this book show the preparation protocols and physiochemical and biological properties of the innovated nanoparticles, designated for different purposes. This is in line with the potential hazards of these materials. The book collection shows that nanoparticles and nanoparticle-based systems can be developed to serve different purposes in the field of animal production and veterinary, such as the management of reproduction and assisted reproductive techniques, rapid and robust disease diagnosis and treatment, drug delivery, and animal nutrition.

Keywords

Technology: general issues --- artificial-insemination --- GnRH --- nanotechnology --- ovulation --- rabbit --- endometritis --- cell receptors --- signaling pathways --- PAMP --- biomolecules --- cytokines --- nanotherapy --- dairy cow --- nanosystem --- biofilm --- mastitis pathogens --- bovine mastitis --- silver nanoparticles --- copper nanoparticles --- silver-copper complex --- nanominerals --- manufacturing --- bioavailability --- hazards --- health --- livestock --- nano-delivery system --- reproductive management --- bio stimulation --- nutrition --- hormones --- antibiotics --- reproductive diseases --- biotechnology --- toxicity --- aquaculture --- poultry --- antibacterial --- antibiotic --- mechanisms --- reactive oxygen species --- zinc oxide nanoparticles --- zeolite --- nano-zeolite --- in vitro gas production --- digestibility --- goat --- methane emission --- clay minerals --- Spirulina maxima pectin --- nanoparticles --- porcine --- embryos --- development --- prolactin --- sodium alginate --- egg production --- qPCR --- chickens --- Staphylococcus pseudintermedius --- wound infection --- antimicrobial resistance --- alternative antimicrobial agent --- scar reduction --- Salmonella --- antimicrobial agents --- virulence genes --- resistance genes --- expression --- antioxidant --- cell internalization --- chitosan nanoparticles --- everted intestine --- lipoic acid --- Moringa --- encapsulation --- reproduction --- milk --- fatty acid --- immunoglobulins --- nanodelivery system --- GPG --- estrous synchronization --- blood flow --- ovary


Book
New Insights on Biofilm Antimicrobial Strategies
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.

Keywords

antibiofilm --- antimicrobial agent --- bacteria --- fungi --- polymicrobial biofilm --- microalga --- free fatty acids --- encapsulation --- biofilm --- chronic wounds --- host response --- S100A8/A9 --- dental plaque --- quorum sensing --- microbial resistance --- bacterial adhesion --- blocking effect --- hydrodynamics --- parallel plate flow cell --- carbon nanotubes --- poly(dimethylsiloxane) --- adhesion --- Escherichia coli --- Biofilm --- Public Engagement --- Outreach --- Control Strategies --- Oral Biofilm --- TiO2 nanofibers --- electrospinning --- biofilm prevention and control --- multidrug-resistant bacteria --- biomedical application --- biofilms --- biofilm inhibition --- dental implants --- peri-implantitis --- polyether-ether-ketone --- Pseudomonas aeruginosa --- Candida albicans --- mixed-species biofilm analysis --- flow cytometry --- bacteriophage therapy --- prosthesis related infections --- hardware infections --- left ventricular assist devices --- Acinetobacter baumannii --- antibiotic resistance --- antibiotic tolerance --- persister --- intraspecies community --- EPS matrix --- peptide nucleic acid-fluorescence in situ hybridization --- urinary tract infections --- catheter-associated urinary tract infections --- confocal laser scanning microscopy --- recalcitrance --- biofilm control --- Klebsiella pneumoniae --- KPC and OXA-48-like carbapenemases --- Galleria mellonella infection model --- linear oligoethyleneimine hydrochloride --- bacteriophage --- endotracheal tube --- n/a


Book
Frontiers in Atmospheric Pressure Plasma Technology
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Year: 2022 Publisher: Basel MDPI Books

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Atmospheric pressure plasma discharges have grown rapidly in importance in recent decades, due to the ease in handling and operation, plus their eco-friendly applications, for agriculture, food, medicine, materials and even the automotive and aerospace industries. In this context, the need for a collection of results based on plasma technologies is justified. Moreover, at the international level, the increased number of projects that translated to publications and patents in the multidisciplinary field of plasma-based technology gives researchers the opportunity to challenge their knowledge and contribute to a new era of green services and products that society demands. Therefore, this book, based on the Special Issue of “Frontiers in Atmospheric Pressure Plasma Technology” in the “Applied Physics” section of the journal Applied Sciences, provides results on some plasma-based methods and technologies for novel and possible future applications of plasmas in life sciences, biomedicine, agriculture, and the automotive industry.This book, entitled “Frontiers in Atmospheric Pressure Plasma Technology”, consists of 8 research articles, 2 review articles and 1 editorial. We know that we are only managing to address a small part of what plasma discharge can be used for, but we hope that the readers will enjoy this book and, therefore, be inspired with new ideas for future research in the field of plasma.


Periodical
Antimicrobial Stewardship & Healthcare Epidemiology

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Antimicrobial Stewardship & Healthcare Epidemiology (ASHE) is a fully Gold Open Access journal that invites submissions of original investigations that will contribute to the fields of antimicrobial stewardship and the prevention of healthcare-associated infections, as well as other areas of quality improvement affecting health systems, with the ultimate goal of improving healthcare safety. Covered topics include the following broad areas of interest: infection prevention, antimicrobial stewardship, healthcare epidemiology, diagnostic stewardship, healthcare worker vaccination, public health policy, and occupational health concerns including blood-borne pathogen exposure prevention.

Keywords

antimicrobial stewardship --- infection prevention --- healthcare safety --- healthcare epidemiology --- public health policy --- Cross Infection --- Epidemiological Methods --- Anti-Infective Agents --- Anti-infective agents --- Epidemiology --- Public health --- Community health services --- Social medicine --- Anti-infective agents. --- Epidemiology. --- Antiinfectieux --- Épidémiologie --- Santé publique --- Antiinfectieux. --- Épidémiologie. --- prevention & control --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Microbicides --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agent --- Anti Infective Agents --- Anti Microbial Agent --- Anti Microbial Agents --- Infections --- Parasites --- Epidemiologic Method --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Diseases --- Antiinfective agents --- Antimicrobial agents --- Antimicrobial drugs --- Antimicrobials --- Drugs --- Neighborhood health centers --- Regional medical programs --- methods --- Social medicine. --- Public health. --- Community health services. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Medical care --- Medical sociology --- Medicine, Social --- Medicine --- Public welfare --- Sociology --- Medical ethics --- Medical sociologists --- Social aspects


Book
Bacteriophages : Alternatives to Antibiotics and Beyond
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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There is talk of an upcoming antibiotic armageddon, with untreatable post-operative infections, and similarly untreatable complications after chemotherapy. Indeed, the now famous “O’Neill Report” (https://amr-review.org/) suggests that, by 2050, more people might die from antibiotic-resistant bacterial infections than from cancer. While we are still learning all the subtle drivers of antibiotic resistance, it seems increasingly clear that we need to take a “one health” approach, curtailing the use of antibiotics in both human and veterinary medicine. However, there are no new classes of antibiotics on our horizon. Maybe something that has been around “forever” can come to our rescue—bacteriophages! Nevertheless, it is also necessary to do things differently, and use these new antimicrobials appropriately. Therefore, an in-depth study of bacteriophage biology and case-by-case applications might be required. Whilst by no means comprehensive, this book does cover some of the many topics related to bacteriophages as antimicrobials, including their use in human therapy and aquaculture. It also explores the potential use of phage endolysins as substitutes of antibiotics in two sectors where there is an urgent need—human therapy and the agro-food industry. Last but not least, there is an excellent perspective article on phage therapy implementation.

Keywords

bacteriophages --- dairy industry --- pathogens --- lactic acid bacteria --- fermentation failure --- biofilms --- antimicrobial resistance --- antimicrobials --- lysins --- horizontal gene transfer, transduction --- biofilm --- phage therapy --- resistance --- bacteriophage --- models --- agent based --- mass action --- bacterial phage resistance --- regression modeling --- MRSA --- Clostridium difficile --- Clostridium difficile infection --- microbiome --- in vitro fermentation model --- marine vibrios --- biological control --- aquaculture --- interactions --- vibriosis --- Aeromonas hydrophila --- Motile Aeromonas Septicemia --- MAS --- multiple-antibiotic-resistance --- striped catfish (Pangasianodon hypophthalmus) --- endolysin --- antibiotics --- one health --- protein engineering --- Aeromonas salmonicida --- furunculosis --- phage-resistant mutants --- proteins --- infrared spectroscopy --- lysin --- lytic enzyme --- peptidoglycan hydrolase --- antimicrobial --- antibacterial --- antibiotic resistance --- bacteriophage therapy --- Nagoya Protocol --- CRISPR CAS --- phage isolation --- phage resistance --- Staphylococcus --- Kayvirus --- Vibrio anguillarum --- fish larvae --- challenge trials --- phage display --- enzybiotics --- Bacteriophages --- diabetic foot ulcer --- osteomyelitis --- Staphylococcus aureus --- Antibiotic-resistant bacteria --- lysogenic conversion --- prophage induction --- read recruitment --- shiga toxin --- American Foulbrood --- phage --- Paenibacillus larvae --- Brevibacillus laterosporus --- treatment --- safety --- bystander phage therapy --- Mycobacterium smegmatis --- mycobacteriophages --- directed evolution --- PlyC CHAP --- protein net charge --- CBD-independent --- FoldX --- STEC-specific bacteriophage --- whole genome sequencing --- STEC O145 strains --- antimicrobial agent --- Pseudomonas aeruginosa --- dual-species --- antibiotic --- synergy --- simultaneous --- sequential --- microbiome therapy --- evolution


Book
A Practical Handbook on the Pharmacovigilance of Antimalarial Medicines
Author:
ISBN: 9241547499 9786612250057 1282250051 9240683712 Year: 2008 Publisher: Geneva : World Health Organization,

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""The Handbook"" is a detailed manual giving a step by step approach to undertaking the pharmacovigilance of antimalarials. It is intended to be a source of practical advice for pharmacovigilance centres. It provides information on spontaneous reporting of adverse drug reactions as a complement to other WHO publications. In addition, it provides details on how to conduct cohort event monitoring, which is a method of active safety surveillance collecting information on all adverse events occurring after treatment. It also details how to perform causality assessment and signal identification, ap

Keywords

Adverse Drug Reaction Reporting Systems. --- Antimalarials -- standards. --- Antimalarials. --- Drug Monitoring. --- Drug Utilization Review -- methods. --- Pharmacoepidemiology -- methods. --- Product Surveillance, Postmarketing. --- Drug monitoring --- Antimalarials --- Drug Monitoring --- Drug Utilization Review --- Product Surveillance, Postmarketing --- Adverse Drug Reaction Reporting Systems --- Pharmacoepidemiology --- Methods --- Utilization Review --- Antiprotozoal Agents --- Investigative Techniques --- Drug Utilization --- Pharmacology --- Epidemiology --- Evaluation Studies as Topic --- Monitoring, Physiologic --- Quality of Health Care --- Quality Assurance, Health Care --- Public Health --- Health Occupations --- Biological Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diagnostic Techniques and Procedures --- Pharmacy Administration --- Antiparasitic Agents --- Disciplines and Occupations --- Medicine --- Health Services Administration --- Natural Science Disciplines --- Health Care Quality, Access, and Evaluation --- Organization and Administration --- Diagnosis --- Anti-Infective Agents --- Therapeutic Uses --- Health Care --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Side effects --- Pharmaceutical Epidemiology --- Epidemiology, Pharmaceutical --- Epidemiologies, Pharmaceutical --- Pharmaceutical Epidemiologies --- Drug Reaction Reporting Systems, Adverse --- Product Surveillance, Post-Marketing --- Drug Surveillance, Postmarketing --- Evaluation Studies, Postmarketing --- Postmarketing Product Surveillance --- Drug Surveillances, Postmarketing --- Evaluation Study, Postmarketing --- Post-Marketing Product Surveillance --- Post-Marketing Product Surveillances --- Postmarketing Drug Surveillance --- Postmarketing Drug Surveillances --- Postmarketing Evaluation Studies --- Postmarketing Evaluation Study --- Postmarketing Product Surveillances --- Product Surveillance, Post Marketing --- Product Surveillances, Post-Marketing --- Product Surveillances, Postmarketing --- Studies, Postmarketing Evaluation --- Study, Postmarketing Evaluation --- Surveillance, Post-Marketing Product --- Surveillance, Postmarketing Drug --- Surveillance, Postmarketing Product --- Surveillances, Post-Marketing Product --- Surveillances, Postmarketing Drug --- Surveillances, Postmarketing Product --- Schizonticides --- Agents, Antiprotozoal --- Review, Utilization --- Reviews, Utilization --- Utilization Reviews --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Anti-Malarials --- Antimalarial Agents --- Antimalarial Drugs --- Agents, Antimalarial --- Anti Malarials --- Drugs, Antimalarial --- Diagnostic Technics and Procedures --- Technics and Procedures, Diagnostic --- Techniques and Procedures, Diagnostic --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Health Professions --- Health Occupation --- Health Profession --- Occupation, Health --- Occupations, Health --- Profession, Health --- Professions, Health --- Medical Specialities --- Medical Specialties --- Medical Specialty --- Specialities, Medical --- Specialties, Medical --- Specialty, Medical --- Medical Speciality --- Speciality, Medical --- Antiparasitic Drugs --- Antiparasitics --- Parasiticides --- Agents, Antiparasitic --- Drugs, Antiparasitic --- Administration, Pharmacy --- Administrations, Pharmacy --- Pharmacy Administrations --- Quality of Care --- Quality of Healthcare --- Care Qualities --- Care Quality --- Health Care Quality --- Healthcare Quality --- Monitoring, Physiological --- Physiologic Monitoring --- Patient Monitoring --- Monitoring, Patient --- Physiological Monitoring --- Critique --- Evaluation --- Evaluation Indexes --- Evaluation Methodology --- Evaluation Report --- Evaluation Research --- Methodology, Evaluation --- Pre-Post Tests --- Qualitative Evaluation --- Quantitative Evaluation --- Theoretical Effectiveness --- Use-Effectiveness --- Critiques --- Effectiveness, Theoretical --- Evaluation Methodologies --- Evaluation Reports --- Evaluation, Qualitative --- Evaluation, Quantitative --- Evaluations --- Evaluations, Qualitative --- Evaluations, Quantitative --- Indexes, Evaluation --- Methodologies, Evaluation --- Pre Post Tests --- Pre-Post Test --- Qualitative Evaluations --- Quantitative Evaluations --- Report, Evaluation --- Reports, Evaluation --- Research, Evaluation --- Test, Pre-Post --- Tests, Pre-Post --- Use Effectiveness --- Disease --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Public --- Health Care Quality Assessment --- Health Care Quality Assurance --- Healthcare Quality Assessment --- Healthcare Quality Assurance --- Quality Assessment, Healthcare --- Quality Assurance, Healthcare --- Quality Assessment, Health Care --- Assessment, Healthcare Quality --- Assessments, Healthcare Quality --- Assurance, Healthcare Quality --- Assurances, Healthcare Quality --- Healthcare Quality Assessments --- Healthcare Quality Assurances --- Quality Assessments, Healthcare --- Quality Assurances, Healthcare --- Utilization, Drug --- Drug Utilizations --- Utilizations, Drug --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Pharmacologies --- Pharmaceutical Preparations --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Therapeutic Effects --- Effects, Therapeutic --- Uses, Therapeutic --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Microbicides --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agents --- Anti Microbial Agents --- Antemortem Diagnosis --- Diagnoses and Examinations --- Examinations and Diagnoses --- Postmortem Diagnosis --- Antemortem Diagnoses --- Diagnoses --- Diagnoses, Antemortem --- Diagnoses, Postmortem --- Diagnosis, Antemortem --- Diagnosis, Postmortem --- Postmortem Diagnoses --- Administration and Organization --- Administrative Technics --- Administrative Techniques --- Coordination, Administrative --- Logistics --- Supervision --- Technics, Administrative --- Techniques, Administrative --- Administration --- Administrative Coordination --- Administrative Technic --- Administrative Technique --- Technic, Administrative --- Technique, Administrative --- Healthcare Quality, Access, and Evaluation --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Administration, Health Services --- Health Services --- Drug Utilization Evaluation --- Drug-Use Review --- Evaluation, Drug Utilization --- Review, Drug Utilization --- Review, Drug-Use --- Utilization Review, Drug --- Drug Use Review --- Drug Utilization Evaluations --- Drug Utilization Reviews --- Drug-Use Reviews --- Evaluations, Drug Utilization --- Review, Drug Use --- Reviews, Drug Utilization --- Reviews, Drug-Use --- Utilization Evaluation, Drug --- Utilization Evaluations, Drug --- Utilization Reviews, Drug --- Monitoring, Drug --- Therapeutic Drug Monitoring --- Drug Monitoring, Therapeutic --- Monitoring, Therapeutic Drug --- Antimalarial agents --- Drugs --- Therapeutic drug monitoring --- methods --- epidemiology --- pharmacology --- diagnosis --- organization & administration --- Monitoring --- Safety-Based Drug Withdrawals --- Parasites --- Protozoan Infections --- Professional Staff Committees --- Malaria --- Plasmodium --- Antirheumatic Agents --- Sensitivity and Specificity --- Occupations --- Pharmacy Audit --- Audit, Pharmacy --- Pharmacy Audits --- Community Health --- Health, Community --- Preventive Medicine --- Education, Public Health Professional --- Off-Label Use --- Pharmacological and Toxicological Phenomena --- Drug Therapy --- Infection --- Pharmacovigilance --- Antiprotozoal agents --- Patient monitoring --- Chemotherapy --- Analysis --- Testing --- Health Workforce --- Infections --- Anti-Malarial --- Antimalarial --- Antimalarial Agent --- Antimalarial Drug --- Agent, Antimalarial --- Anti Malarial --- Drug, Antimalarial --- Diagnostic Testing --- Testing, Diagnostic --- Antiparasitic --- Social Epidemiology --- Epidemiologies, Social --- Epidemiology, Social --- Social Epidemiologies --- Therapeutic Effect --- Therapeutic Use --- Effect, Therapeutic --- Use, Therapeutic --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Anti Infective Agent --- Anti Microbial Agent --- Diagnose --- Techniques --- Technique

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