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Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus on protein-protein interaction predictions in bacteria. The authors will describe these methods and further highlight its use to predict various biological pathways and complexity of the cellular response to various environmental conditions. Topics include analysis of complex genome-scale protein-protein interaction networks, effects of reference genome selection on prediction accuracy, and genome sequence templates to predict protein function.

Functional genomics. --- Protein-protein interactions. --- Interactions, Protein-protein --- Protein interactions --- Physiological genomics --- Protein-protein interactions --- Bacterial genetics --- Protein Interaction Mapping --- Protein Array Analysis --- Life sciences. --- Human genetics. --- Proteomics. --- Bioinformatics. --- Systems biology. --- Life Sciences. --- Systems Biology. --- Human Genetics. --- Molecular association --- Genomics --- Physiology --- Biological models. --- Molecular biology --- Proteins --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Models, Biological --- Data processing --- Bioinformatics --- Biological systems

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Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards “nanoarrays”, which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.

Cytology. --- DNA microarrays. --- Medicine. --- Protein microarrays. --- DNA microarrays --- Protein microarrays --- Sequence Analysis --- Molecular Probe Techniques --- Investigative Techniques --- Microarray Analysis --- Nucleic Acid Hybridization --- Genetic Techniques --- Microchip Analytical Procedures --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemistry Techniques, Analytical --- Protein Array Analysis --- Oligonucleotide Array Sequence Analysis --- Clinical Laboratory Techniques --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Biomedical Engineering --- Biochemical markers. --- Biologic markers --- Biological markers --- Biomarkers --- Markers, Biochemical --- DNA biochips --- Microarrays, DNA --- Microarrays. --- Cell biology. --- Biomedicine. --- Cell Biology. --- Biochemistry --- Indicators (Biology) --- Biochips --- Immobilized nucleic acids --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists