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"The World Bank coordinated a fight against riverblindness, a parasitic tropical disease, which commenced more than forty years ago. The story of the battle has an epic scale, both in terms of geography and the number of people and organizations involved. The book provides a success story and a bureaucratic template for other global health efforts. The author worked for the World Bank and oversaw its campaign to end riverblindness"--
Onchocerciasis. --- Onchocercosis --- River blindness --- Robles' disease --- Filariasis --- Onchocerciasis Control Programme in West Africa. --- African Programme for Onchocerciasis Control. --- Africa --- Onchocerciasis --- Disease management --- International cooperation. --- Epidemiology.
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This Special Issue explores the range of clinical manifestations and epidemiology of both skin NTDs and common skin disease in endemic regions, the use of common diagnostic and management pathways, the different technologies that play a role in diagnosis and training, the role of patient involvement at a community level, as well as the assessment of the results of different initiatives in the field.
n/a --- topical corticosteroids --- mental health --- digital handheld microscope --- skin infections --- sporotrichosis Community dermatology --- mHealth --- animal reservoir --- iatrogenic --- case management --- Wet Dermatoscopy (w-DS) --- Mycobacterium ulcerans --- transmission --- neglected tropical diseases --- review --- Enhanced Dermatoscopy (e-DS) --- outbreak --- long range diagnosis --- teledermatology --- Treponema pallidum --- leprosy --- onchocerciasis --- mass drug administration --- point of care test --- scabies --- Africa --- podoconiosis --- Mite-Gallery Unit (MGU) --- diagnosis --- Amerindian communities --- eumycetoma --- community engagement --- clinical presentation --- integration --- onchocercal skin disease --- mycetoma --- PCR --- mobile phone application --- stigma --- resource-poor setting --- slit skin smears --- morbidity management --- training --- tele-expertise --- ivermectin --- eHealth --- NTDs --- Dry Dermatoscopy (d-DS) --- Amazon lowland --- actinomycetoma --- patient involvement --- tropical skin diseases --- surveillance --- yaws --- skin diseases --- skin NTDs --- lymphedema --- Cushing syndrome --- onchodermatitis --- skin disease --- primary health care --- technology --- skin biopsy --- impetigo --- early diagnosis --- dermatology --- telepathology --- drought --- subcutaneous mycosis --- disease mapping --- emergency state --- Entodermoscopy (EDS) --- leprosy diagnosis
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The importance of natural products, and especially plant secondary metabolites, for the treatment of diseases and drug development has already been obvious in medicine for several thousand years. Thus, this Special Issue of MDPI Biomedicines collects eight top articles from the field as regular full papers in addition to five reviews. All of the published papers are a vibrant source of information on the therapeutic potential of plant secondary metabolites in the treatment of diseases and drug development.
Cannabis sativa (Cannabis) --- cannabinoids --- tetrahydrocannabinol (THC) --- cannabidiol (CBD) --- cannabinoid receptors (CB1 and CB2) --- Papaver somniferum (opium poppy) --- secondary metabolites --- ursolic acid --- NSCLC --- tumorsphere --- EGFR --- STAT3 --- MMP2 --- PD-L1 --- MAFLD --- tanshinone IIA --- phytochemical --- lipogenesis --- lipid accumulation --- LXRα --- malaria --- quinine --- chloroquine --- artemisinin --- onchocerciasis --- ivermectin --- moxidectin --- cancer --- vincristine --- vinblastine --- anabolic --- diabetes --- Duchenne muscular dystrophy --- β-ecdysone --- ecdysteroid --- ecdysterone --- Mas1 --- osteoporosis --- sarcopenia --- COVID-19 --- cardiometabolic diseases --- respiratory diseases --- natural product --- SARS-CoV-2 --- lung cancer --- United States Food and Drug Administration-approved drug --- natural remedy --- triterpenoid --- molecular ribbon --- Huisgen 1,3-dipolar cycloaddition --- amide bond --- multifunctional PEG3 derivative --- antimicrobial activity --- anti-HIV activity --- cytotoxicity --- supramolecular self-assembly --- phytocannabinoids --- cannabichromene --- thermos-TRPs --- TRPA1 --- α,α-dimethylheptyl effect --- betulinic acid --- BODIPY --- bevirimat --- cell-cycle --- fluorescent microscopy --- maturation inhibitor --- capsaicinoids --- endocannabinoidome --- microbiota --- overweight --- obesity --- food intake --- lipidomics --- metabolism --- alkaloids --- membrane fusion --- viral fusion inhibitor --- antiviral therapy --- curcumin --- cancer cells --- bioavailability --- curcumin derivatives --- curcumin analogues --- curcumin delivery systems --- natural product synthesis --- lignans --- inflammation --- NF-κB inhibition --- n/a
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In this book is reported novel information on diagnosis, treatment, and control of parasites that are naturally transmitted from animal reservoirs to humans. Subjects: Public Health and Healthcare: Prevention; Medicine and Pharmacology: Therapy.
canine vector-borne disease --- blocking primers --- blood DNA extraction --- next-generation sequencing --- kit contaminant bacteria --- mosquito-borne disease --- pest control --- insecticide resistance --- biological control --- paratransgenesis --- Wolbachia --- Asaia --- Bacillus --- Strongyloides stercoralis --- soil-transmitted helminths --- hookworms --- zoonotic parasites --- Australian remote communities --- One Health --- biting midges --- vector --- mitochondrial cytochrome oxidase subunit I --- C. gornostaevae --- C. griseidorsum --- C. pallidicornis --- onchocerciasis --- Onchocerca volvulus --- antibodies --- diagnosis --- OV16 testing --- microfilariae --- epilepsy --- Dirofilaria immitis --- modified Knott’s test --- ELISA --- immune complex dissociation --- serological assays --- bacterial profile --- cox1 --- Haemaphysalis bancrofti --- Ixodes holocyclus --- Ixodes trichosuri --- Ixodes tasmani --- V3-V4 16S rRNA gene --- mosquito virome --- CRESS-DNA viruses --- CyCV-VN --- insect-specific viruses --- ISV --- BatCV --- Leishmania --- protozoan parasite --- epidemiology --- environment --- Toxocara --- multiple sclerosis --- association --- meta-analysis --- Transphlebotomus --- Central Europe --- autoimmunofluorescence --- MALDI-TOF mass spectrometry --- genotyping --- leishmaniasis --- Polygonum salicifolium --- chalcone --- flavanone --- Leishmania mexicana --- Trypanosoma brucei brucei --- Trypanosoma congolense --- Canis lupus --- Vulpes vulpes --- Sarcoptes scabiei --- PCR --- serology --- Iberian Peninsula --- toxoplasmosis --- animals --- native antigens --- recombinant antigens --- Echinococcus --- NaOH --- LAMP --- DNA extraction --- taeniid egg isolation --- schistosomiasis --- Schistosoma japonicum --- right open reading frame protein kinase (riok) genes --- riok-1 --- RIOK-1 --- double-stranded RNA interference (RNAi) --- chemical inhibition --- toyocamycin --- developmental and reproductive biology --- blood filter paper --- Chagas disease --- Nobuto strip --- Trypanosoma cruzi --- mammalian surveillance --- neglected tropical diseases --- Culex pipiens s. l. --- Culex torrentium --- Culiseta glaphyroptera --- caves --- subterranean environment --- Luxembourg --- Germany --- n/a --- modified Knott's test
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