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Book
Riverblindness in Africa
Author:
ISBN: 1421439662 1421439670 9781421439679 9781421439662 Year: 2020 Publisher: Baltimore

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Abstract

"The World Bank coordinated a fight against riverblindness, a parasitic tropical disease, which commenced more than forty years ago. The story of the battle has an epic scale, both in terms of geography and the number of people and organizations involved. The book provides a success story and a bureaucratic template for other global health efforts. The author worked for the World Bank and oversaw its campaign to end riverblindness"--


Book
Skin-Related Neglected Tropical Diseases (Skin-NTDs)—A New Challenge
Authors: ---
ISBN: 3039212540 3039212532 Year: 2019 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This Special Issue explores the range of clinical manifestations and epidemiology of both skin NTDs and common skin disease in endemic regions, the use of common diagnostic and management pathways, the different technologies that play a role in diagnosis and training, the role of patient involvement at a community level, as well as the assessment of the results of different initiatives in the field.


Book
Therapeutic Potential of Plant Secondary Metabolites in the Treatment of Diseases and Drug Development
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The importance of natural products, and especially plant secondary metabolites, for the treatment of diseases and drug development has already been obvious in medicine for several thousand years. Thus, this Special Issue of MDPI Biomedicines collects eight top articles from the field as regular full papers in addition to five reviews. All of the published papers are a vibrant source of information on the therapeutic potential of plant secondary metabolites in the treatment of diseases and drug development.

Keywords

Cannabis sativa (Cannabis) --- cannabinoids --- tetrahydrocannabinol (THC) --- cannabidiol (CBD) --- cannabinoid receptors (CB1 and CB2) --- Papaver somniferum (opium poppy) --- secondary metabolites --- ursolic acid --- NSCLC --- tumorsphere --- EGFR --- STAT3 --- MMP2 --- PD-L1 --- MAFLD --- tanshinone IIA --- phytochemical --- lipogenesis --- lipid accumulation --- LXRα --- malaria --- quinine --- chloroquine --- artemisinin --- onchocerciasis --- ivermectin --- moxidectin --- cancer --- vincristine --- vinblastine --- anabolic --- diabetes --- Duchenne muscular dystrophy --- β-ecdysone --- ecdysteroid --- ecdysterone --- Mas1 --- osteoporosis --- sarcopenia --- COVID-19 --- cardiometabolic diseases --- respiratory diseases --- natural product --- SARS-CoV-2 --- lung cancer --- United States Food and Drug Administration-approved drug --- natural remedy --- triterpenoid --- molecular ribbon --- Huisgen 1,3-dipolar cycloaddition --- amide bond --- multifunctional PEG3 derivative --- antimicrobial activity --- anti-HIV activity --- cytotoxicity --- supramolecular self-assembly --- phytocannabinoids --- cannabichromene --- thermos-TRPs --- TRPA1 --- α,α-dimethylheptyl effect --- betulinic acid --- BODIPY --- bevirimat --- cell-cycle --- fluorescent microscopy --- maturation inhibitor --- capsaicinoids --- endocannabinoidome --- microbiota --- overweight --- obesity --- food intake --- lipidomics --- metabolism --- alkaloids --- membrane fusion --- viral fusion inhibitor --- antiviral therapy --- curcumin --- cancer cells --- bioavailability --- curcumin derivatives --- curcumin analogues --- curcumin delivery systems --- natural product synthesis --- lignans --- inflammation --- NF-κB inhibition --- n/a


Book
Translational Research for Zoonotic Parasites: New Findings toward Improved Diagnostics, Therapy and Prevention
Author:
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

In this book is reported novel information on diagnosis, treatment, and control of parasites that are naturally transmitted from animal reservoirs to humans. Subjects: Public Health and Healthcare: Prevention; Medicine and Pharmacology: Therapy.

Keywords

canine vector-borne disease --- blocking primers --- blood DNA extraction --- next-generation sequencing --- kit contaminant bacteria --- mosquito-borne disease --- pest control --- insecticide resistance --- biological control --- paratransgenesis --- Wolbachia --- Asaia --- Bacillus --- Strongyloides stercoralis --- soil-transmitted helminths --- hookworms --- zoonotic parasites --- Australian remote communities --- One Health --- biting midges --- vector --- mitochondrial cytochrome oxidase subunit I --- C. gornostaevae --- C. griseidorsum --- C. pallidicornis --- onchocerciasis --- Onchocerca volvulus --- antibodies --- diagnosis --- OV16 testing --- microfilariae --- epilepsy --- Dirofilaria immitis --- modified Knott’s test --- ELISA --- immune complex dissociation --- serological assays --- bacterial profile --- cox1 --- Haemaphysalis bancrofti --- Ixodes holocyclus --- Ixodes trichosuri --- Ixodes tasmani --- V3-V4 16S rRNA gene --- mosquito virome --- CRESS-DNA viruses --- CyCV-VN --- insect-specific viruses --- ISV --- BatCV --- Leishmania --- protozoan parasite --- epidemiology --- environment --- Toxocara --- multiple sclerosis --- association --- meta-analysis --- Transphlebotomus --- Central Europe --- autoimmunofluorescence --- MALDI-TOF mass spectrometry --- genotyping --- leishmaniasis --- Polygonum salicifolium --- chalcone --- flavanone --- Leishmania mexicana --- Trypanosoma brucei brucei --- Trypanosoma congolense --- Canis lupus --- Vulpes vulpes --- Sarcoptes scabiei --- PCR --- serology --- Iberian Peninsula --- toxoplasmosis --- animals --- native antigens --- recombinant antigens --- Echinococcus --- NaOH --- LAMP --- DNA extraction --- taeniid egg isolation --- schistosomiasis --- Schistosoma japonicum --- right open reading frame protein kinase (riok) genes --- riok-1 --- RIOK-1 --- double-stranded RNA interference (RNAi) --- chemical inhibition --- toyocamycin --- developmental and reproductive biology --- blood filter paper --- Chagas disease --- Nobuto strip --- Trypanosoma cruzi --- mammalian surveillance --- neglected tropical diseases --- Culex pipiens s. l. --- Culex torrentium --- Culiseta glaphyroptera --- caves --- subterranean environment --- Luxembourg --- Germany --- n/a --- modified Knott's test

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