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This volume provides a comprehensive description of the principles and methods used in DNA sequencing. Following a detailed introduction the chapters are: DNA sequencing; Chain terminator sequencing; Primed synthesis methods applied to DNA fragments cloned into phage M13; DNA sequencing by the Maxam-Gilbert chemical procedure; Computer methods for DNA sequencers; Appendices including contractions and special terms, cloning vectors, commercially available restriction endonucleases, and autoradiography.

Analytical biochemistry --- Molecular biology --- Dna --- Nucleotide sequence. --- Base sequence. --- Dna. --- Analysis. --- DNA --- Nucleotide sequence --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Sequence, Nucleotide --- Nucleic acids --- Nucleotides --- Sequence alignment (Bioinformatics) --- Analysis

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Le livre traite de façon pratique et exhaustive des nombreuses applications de la biologie moléculaire en médecine. Il est divisé en trois parties : la première expose les concepts de base en biologie moléculaire, concepts qu'il faut avoir acquis pour comprendre les applications de la discipline à la pathologie humaine ; ces dernières sont largement détaillées dans la seconde partie ; la troisième est consacrée à l'exposé des méthodes utilisées en biologie moléculaire ; l'ouvrage se termine par un glossaire très détaillé comportant la définition claire et précise de tous les termes de la discipline, et par un important index. Il n'a pas d'équivalent français ou étranger.

moleculaire biologie --- moleculaire geneeskunde --- genetische engineering (manipulatie) --- biologie moléculaire --- médecine moléculaire --- génie génétique (ingénierie génétique) --- Molecular Biology --- Molecular biology --- Biologie moléculaire --- Gene amplification. --- Genetic markers. --- Molecular biology. --- Base sequence --- Cloning, molecular --- Genetic vectors --- Genome --- Nucleic acid hybridization

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Computer. Automation --- genen --- Biomathematics. Biometry. Biostatistics --- moleculaire biologie --- proteïnen --- biocomputing --- Computational Biology --- Base Sequence --- Sequence Analysis --- Protein --- Nucleotide sequence --- Amino acid sequence --- Genes --- Proteins --- Séquence nucléotidique --- Séquence des acides aminés --- Gènes --- Protéines --- methods --- analysis --- Databases --- Data processing --- Analysis --- Bases de données --- Informatique --- Analyse --- -Nucleotide sequence --- -681.3*J3 --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Analysis, Nucleic acid sequence --- Analysis, Nucleotide sequence --- Base sequence (Nucleic acids) --- DNA sequence --- Nucleic acid sequence analysis --- Nucleotide sequence analysis --- RNA sequence --- Sequence, Nucleotide --- Nucleic acids --- Nucleotides --- Sequence alignment (Bioinformatics) --- Units of heredity --- Units of inheritance --- Heredity --- Molecular genetics --- DNA --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Amino acids --- -Data processing --- Life and medical sciences (Computer applications) --- 681.3*J3 Life and medical sciences (Computer applications) --- Séquence nucléotidique --- Séquence des acides aminés --- Gènes --- Protéines --- Bases de données --- 681.3*J3 --- Analysis&delete& --- Base Sequence. --- methods. --- analysis. --- -Analysis

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Molecular biology --- Computer. Automation --- Amino acid sequence --- Amino Acid Sequence --- Automatic Data Processing --- Base Sequence --- Data processing --- Amino Acid Sequence. --- Automatic Data Processing. --- Base Sequence. --- -57.088.1 --- 577.112 --- 577.113 --- Amino acid sequence analysis --- Analysis, Amino acid sequence --- Peptide sequence --- Peptide sequencing --- Protein sequence --- Protein sequencing --- Sequence, Amino acid --- Amino acids --- Proteins --- Sequence alignment (Bioinformatics) --- DNA Sequences --- DNA Sequence --- Nucleotide Sequence --- RNA Sequence --- Base Sequences --- Nucleotide Sequences --- RNA Sequences --- Sequence, Base --- Sequence, DNA --- Sequence, Nucleotide --- Sequence, RNA --- Sequences, Base --- Sequences, DNA --- Sequences, Nucleotide --- Sequences, RNA --- Genes --- Nucleotides --- Information Processing --- Bar Codes --- Computer Data Processing --- Data Processing, Automatic --- Electronic Data Processing --- Information Processing, Automatic --- Optical Readers --- Automatic Information Processing --- Bar Code --- Code, Bar --- Codes, Bar --- Data Processing, Computer --- Data Processing, Electronic --- Optical Reader --- Processing, Automatic Data --- Processing, Automatic Information --- Processing, Computer Data --- Processing, Electronic Data --- Processing, Information --- Reader, Optical --- Readers, Optical --- Computers --- Amino Acid Sequences --- Sequence, Amino Acid --- Sequences, Amino Acid --- Protein Structure, Primary --- Primary Protein Structure --- Primary Protein Structures --- Protein Structures, Primary --- Structure, Primary Protein --- Structures, Primary Protein --- Peptides --- Methods for analysis and estimation --- Nucleic acids --- Analysis --- Basic Sciences. Molecular Biology --- Nucleotide sequence --- AUTOMATIC DATA PROCESSING --- Amino acid sequence. --- Base sequence --- Nucleic Acids --- Data processing. --- AUTOMATIC DATA PROCESSING. --- Base sequence. --- Nucleic Acids. --- 577.113 Nucleic acids --- 577.112 Proteins --- 57.088.1 Methods for analysis and estimation --- Automatic data processing. --- Basic sciences. molecular biology --- Nucleic acids. --- 57.088.1 --- Amino acid sequence - Data processing

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Mitochondrial DNA --- DNA, Mitochondrial. --- Base Sequence. --- Mitochondrial DNA. --- mtDNA --- Extrachromosomal Inheritance --- Genes, Mitochondrial --- Mitochondrial genome --- Mitochondrial genomes --- Extrachromosomal DNA --- DNA Sequences --- DNA Sequence --- Nucleotide Sequence --- RNA Sequence --- Base Sequences --- Nucleotide Sequences --- RNA Sequences --- Sequence, Base --- Sequence, DNA --- Sequence, Nucleotide --- Sequence, RNA --- Sequences, Base --- Sequences, DNA --- Sequences, Nucleotide --- Sequences, RNA --- Genes --- Nucleotides --- Animal Biochemistry