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Bodily Secretions --- Lenses --- Lacrimal Apparatus Diseases --- Eye Diseases --- Optical Devices --- Fluids and Secretions --- Anatomy --- Diseases --- Equipment and Supplies --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Dry Eye Syndromes --- Tears --- Contact Lenses
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Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry,
Transport theory --- Tissues --- Cells --- Biological transport --- Metabolism --- Models, Theoretical --- Fluids and Secretions --- Investigative Techniques --- Metabolic Phenomena --- Anatomy --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Transport --- Body Fluids --- Models, Biological --- Biology --- Health & Biological Sciences --- Biophysics --- Mechanical properties --- Biological transport. --- Membrane transport --- Passive transport, Biological --- Physiological transport --- Transport, Biological --- Diffusion --- Osmosis --- Transport theory. --- Mechanical properties.
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High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies is an authoritative reference on the current state-of-the-art in sample preparation techniques for bioanalysis. This book focuses on high throughput (rapid productivity) techniques and describes exactly how to perform and automate these methodologies, including useful strategies for method development and optimization. A thorough review of the literature is included within each of these chapters describing high throughput sample preparation techniques: protein removal by precipitation; equilibrium dialysis and ultrafiltration; liquid-liquid extraction; solid-phase extraction; and various on-line techniques. The text begins with an introductory overview of the role of bioanalysis in pharmaceutical drug development. Fundamental understanding of the strategies for sample preparation is reinforced next, along with essential concepts in extraction chemistry. Several chapters introduce and discuss microplates, accessory products and automation devices. Particular strategies for efficient use of automation within a bioanalytical laboratory are also presented. The subject material then reviews protein precipitation, liquid-liquid extraction, solid-phase extraction and various on-line sample preparation approaches. The book concludes with information on recent advances in sample preparation, such as solid-phase extraction in a card format and higher density extraction plates. Important objectives that can be accomplished when the strategies presented in this book are followed include: improved efficiency in moving discovery compounds to preclinical status with robust analytical methods; return on investment in automation for sample preparation; and improved knowledge and expertise of laboratory staff. Shows the reader exactly how to perform modern bioanalytical sample preparation techniques, complete with detailed strategies Thorough literature review and summary of published information Detailed discussion and examples of the method development process.
Drugs --- Pharmaceutical industry --- Metabolic Phenomena --- Pharmacological Phenomena --- Kinetics --- Natural Science Disciplines --- Investigative Techniques --- Fluids and Secretions --- Chemicals and Drugs --- Evaluation Studies as Topic --- Drug Discovery --- Body Fluids --- Chemistry --- Methods --- Drug Evaluation, Preclinical --- Chemistry Techniques, Analytical --- Metabolism --- Pharmacokinetics --- Pharmaceutical Preparations --- Biochemical Phenomena --- Phenomena and Processes --- Physiological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Anatomy --- Disciplines and Occupations --- Chemical Phenomena --- Analysis --- Technological innovations
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Fluid disorders play a role in nearly every patient's presentation and can sometimes be the key to understanding an uncertain or difficult case. This unique resource clearly and comprehensively describes the Traditional Chinese Medicine view of the physiology and pathology of fluids within the body. Covers disorders of sweating and urination, edema, abnormal lacrimation, thin mucus syndrome, and conditions of excessive phlegm and dampness in the body, such as asthma, digestive problems, arthritis, epilepsy, and convulsions. Features over 20 new case histories and essays that illustrate the Traditional Chinese Medicine approach to the treatment of fluid disorders using Chinese herbs, acupuncture, and more. A complete index provides reference to specific disorders, concepts, formulas, and points. A new chapter on Acupuncture Methods in Fluid Pathology details acupuncture treatments for specific disorders of fluid metabolism. New case histories illustrate theoretical concepts and demonstrate their use in the clinic, as well as assist in developing a sense of prognosis and occasionally an alternative approach to a difficult case. An in-depth description of the Traditional Chinese Medicine concept of body fluid physiology and pathology conveys an essential understanding of fluid disorders and their role in every patient's clinical presentation, which may be the key to an otherwise uncertain or difficult case. Both Chinese herbal treatments and acupuncture methodologies are described for each fluid disorder, bringing theory into practical use.
Body fluid disorders --- Body fluids --- Medicine, Chinese --- Medicine, East Asian Traditional --- Fluids and Secretions --- Health Occupations --- Biological Science Disciplines --- Anatomy --- Disciplines and Occupations --- Medicine, Traditional --- Natural Science Disciplines --- Complementary Therapies --- Culture --- Therapeutics --- Anthropology, Cultural --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Anthropology --- Social Sciences --- Anthropology, Education, Sociology and Social Phenomena --- Physiology --- Body Fluids --- Medicine, Chinese Traditional --- Acupuncture
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Blood -- Transfusion. --- Burns and scalds -- Surgery. --- Blood --- Burns and scalds --- Body Fluids --- Biological Therapy --- Fluids and Secretions --- Therapeutics --- Blood Transfusion --- Anatomy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Health & Biological Sciences --- Hematologic Diseases --- Transfusion --- Surgery --- Transfusion. --- Surgery. --- Burn trauma --- Scalds --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Wounds and injuries --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Transfusion committees
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This book summarizes the most recent progress in the studies of lipid mediators from the molecular to clinical level and introduces newly created tools for analysis including imaging mass spectrometry. Comprising 29 chapters divided into four major parts, the book describes the molecular natures of enzymes, transporters, and receptors for lipid mediators (Part I), the function of lipid mediators in Drosophila and Zebrafish (Part II), the relationships between lipid mediators and various diseases (Part III), and detailed procedures of extraction, preparation, and quantification of lipid mediators (Part IV). Research on lipid mediators initially started with analysis of the action of aspirin, and subsequent biochemical experiments identified many enzymes and receptors responsible for the biosynthesis and signal transduction of individual lipid mediators. Through the phenotypic analyses of transgenic and knockout mice, it has been shown that the dysregulation of some lipid mediators causes inflammatory, immune, or oncogenic disorders. Lipid mediators have attracted increased attention because their structures are conserved among different species, and their biosynthetic and signaling pathways have been deciphered at the molecular level. Many drugs that target lipid mediators are already being used in hospitals, and this book suggests further possibilities for development of a wide variety of such drugs. Very recently, highly sensitive mass spectrometry has begun to be used to identify novel lipid mediators that are present only in trace amounts in tissues but with robust biological activity. Written by international experts, this book provides readers a comprehensive view of lipid mediators and related topics and helps in the process of determining research targets for the near future.
Human physiology. --- Lipids --- Pharmacology --- Blood --- Signal Transduction --- Biological Transport --- Metabolism --- Chemicals and Drugs --- Body Fluids --- Biochemical Processes --- Biochemical Phenomena --- Fluids and Secretions --- Metabolic Phenomena --- Phenomena and Processes --- Anatomy --- Chemical Phenomena --- Biochemistry --- Biology - General --- Biology --- Chemistry --- Physical Sciences & Mathematics --- Health & Biological Sciences --- Synthesis --- Research --- Technique. --- Synthesis. --- Lipid synthesis --- Lipides --- Lipins --- Lipoids --- Life sciences. --- Lipids. --- Cell biology. --- Life Sciences. --- Lipidology. --- Cell Biology. --- Human Physiology. --- Biomolecules --- Steroids --- Cytology. --- Human biology --- Medical sciences --- Physiology --- Human body --- Cell biology --- Cellular biology --- Cells --- Cytologists
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This original six chapter book will briefly review and integrate the basic concepts behind water distribution and movement in the body. This fills a knowledge gap that most medical and undergraduate physiology students acquire when these topics are studied separately. As of now, there is no textbook that fully integrates renal, cardiovascular and water physiology in a clear understandable manner. The book is intended primarily for medical students and undergraduate physiology students. Chapters include: 1) Water and its Distribution; 2) Water Dynamics; 3) Fluid Handling by the Heart and Blo
Human anatomy. --- Human physiology. --- Body fluids --- Cardiovascular system --- Urinary organs --- Circulatory and Respiratory Physiological Phenomena --- Anatomy --- Fluids and Secretions --- Phenomena and Processes --- Urogenital System --- Body Fluids --- Cardiovascular Physiological Phenomena --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Body fluids. --- Cardiovascular system. --- Urinary organs. --- Urinary tract --- Genitourinary organs --- Circulatory system --- Vascular system --- Blood --- Animal fluids and humors --- Body humors --- Fluids, Body --- Fluids and humors, Animal --- Humors, Body --- Circulation --- Water in the body. --- Blood water.
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Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences. In the last several years, extracellular nucleic acids have been shown to be involved in not only microbial evolution as genetic elements but also to have structural roles in bacterial communities, such as biofilms. Circulating DNA and RNA have been found in human blood and expected to be useful as non-invasive markers for the diagnosis of several diseases. In addition, extracellular nucleic acids have attracted attention as active modulators of the immune system of higher organisms, including humans. This book covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them.
Nucleic Acids -- Chemistry. --- Nucleic Acids -- Physiology. --- Nucleic Acids -- Therapeutic use. --- Nucleic acids. --- Nucleic acids --- Body Fluids --- Nucleic Acids, Nucleotides, and Nucleosides --- Extracellular Space --- Fluids and Secretions --- Cellular Structures --- Chemicals and Drugs --- Extracellular Fluid --- Nucleic Acids --- Cells --- Anatomy --- Human Anatomy & Physiology --- Biology --- Health & Biological Sciences --- Cytology --- Animal Biochemistry --- Polynucleotides --- Life sciences. --- Biochemistry. --- Cell biology. --- Life Sciences. --- Cell Biology. --- Biochemistry, general. --- Biomolecules --- Cytology. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Cell biology --- Cellular biology --- Cytologists --- Composition
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Fluid, electrolyte, and acid-base disorders are central to the day-to-day practice of almost all areas of patient-centered medicine – both medical and surgical. Virtually every aspect of these disorders has experienced major developments in recent years. Core Concepts in the Disorders of Fluid, Electrolytes and Acid-Base Balance encompasses these new findings in comprehensive reviews of both pathophysiology and clinical management. In addition, this volume offers clinical examples providing step-by-step analysis of the pathophysiology, differential diagnosis, and management of selected clinical problems. Written by the leaders in researching and treating electrolyte disorders, this reference is an invaluable resource for both the nephrologist and the non-specialist physician, or medical trainee.
Acid-base imbalance. --- Body fluid disorders. --- Body fluids. --- Water-electrolyte imbalances. --- Water-electrolyte imbalances --- Body fluid disorders --- Metabolic Diseases --- Fluids and Secretions --- Anatomy --- Nutritional and Metabolic Diseases --- Diseases --- Acid-Base Imbalance --- Water-Electrolyte Imbalance --- Body Fluids --- Medicine --- Health & Biological Sciences --- Urology & Nephrology --- Metabolic & Nutritional Diseases --- Electrolyte disorders --- Electrolyte-water imbalances --- Imbalances, Water-electrolyte --- Water-electrolyte imbalance --- Body fluid imbalances --- Fluid balance disorders --- Medicine. --- Internal medicine. --- Nephrology. --- Medicine & Public Health. --- Internal Medicine. --- Metabolism --- Disorders --- Medicine, Internal --- Internal medicine --- Kidneys
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This publication aims to provide practical guidance to all those involved in the management of blood programmes. Following an introduction to the blood cold chain management process, seven chapters provide a detailed description of blood bank refrigerators, plasma freezers, platelet agitators, plasma thawing equipment, blood transport boxes and coolants, temperature monitoring devices, as well as other blood cold chain accessories. Each chapter provides WHO minimum performance specifications for the equipment, and selected product information on equipment evaluated by WHO. A specific chapter i
Bloedplaatjes --- Bloedplasma --- Blood plasma --- Blood platelets --- Blood--Plasma --- Plaatjes [Bloed] --- Plaquettes sanguines --- Plasma (Bloed) --- Plasma (Blood) --- Plasma (Sang) --- Plasma sanguin --- Platelets --- Thrombocytes --- Trombocyten --- Blood. --- Blood --- Blood banks --- Hematologic equipment industry --- Tissue Preservation --- Preservation, Biological --- Biological Specimen Banks --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Blood Cells --- Health Facilities --- Investigative Techniques --- Body Fluids --- Cells --- Specimen Handling --- Laboratory Techniques and Procedures --- Fluids and Secretions --- Anatomy --- Health Care Facilities, Manpower, and Services --- Diagnosis --- Health Care --- Refrigeration --- Blood Platelets --- Blood Banks --- Blood Preservation --- Equipment and Supplies --- Plasma --- Medicine --- Health & Biological Sciences --- Hematologic Diseases --- Equipment and supplies --- Collection and preservation --- Transfusion --- Refrigerators. --- Equipment and supplies. --- Refrigeration and refrigerating machinery --- Body fluids --- Fear of blood --- Standards --- Guidebooks
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