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The development of new foods or nutraceuticals with health benefits is among today’s most important issues, which presents an opportune moment for the food and/or pharmaceutical industries. However, the launch of new products should be supported by strong scientific evidence on the health benefits attributable to the intake of these bioactive food ingredients. Studies focusing on changes during the storage conditions, digestion process, intestinal absorption rates, biological mechanisms of action, or bioactivity of their metabolites are also required to establish the real contribution of these compounds to the health status of today’s societies

phytochemicals --- antioxidant --- antinausea --- antiobesity --- anticancer --- anti-inflammatory --- ‘Cara Cara’ juice --- storage --- hydrophilic and lipophilic antioxidant --- carotenoid --- flavonoid --- degradation --- dried distilled spent grain (DDSG) --- melanoidins --- content --- structure --- antioxidant activity --- ACE-inhibitory activity --- beverages --- brewing method --- antioxidant potential --- total polyphenols content --- mineral composition --- grape stem --- phenolic compounds --- central composite rotatable design --- sustainable food systems --- pressurized liquid extraction --- side streams valorisation --- curcumin --- milk proteins --- nanoparticles --- antimicrobial activities --- bioactive peptides --- hypertension --- functional food --- metabolic syndrome --- microbiota --- insulin sensitivity --- polyphenols --- grape pomace --- donkey milk (DM) --- donkey colostrum (DC) --- mammal’s milk --- cow’s milk protein allergy (CMPA) --- biologic activity --- immunosenescence --- health benefits --- cryoconcentration --- calafate juice --- storage time --- physicochemical properties --- bioactive compounds --- sensorial analysis --- apitherapy --- royal jelly --- propolis --- bee pollen --- sarcopenia --- dietary interventions --- muscle --- skeletal --- muscle wasting --- physical performance --- coronavirus disease 2019 --- COVID-19 --- body composition --- lean body mass --- insulin resistance --- mitochondrial dysfunction --- satellite stem cells --- polysaccharide purification --- anti-obesity --- proliferation --- PPARγ --- biological activities --- isolation --- analysis --- mechanism of action --- bioaccessibility --- intestinal absorption --- bioavailability

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The landscape of minimally invasive urological intervention is changing. A lot of new innovations and technological developments have happened over the last 3 decades. Laparoscopy and robotic surgery have revolutionised kidney and prostate cancer treatment, with more minimally invasive procedures now being carried out than ever before. At the same time, technological advancements and the use of laser have changed the face of endourology. Several new innovative treatments are now commonplace for benign prostate enlargement (BPE). Management of prostate cancer now involves procedures such as robotic prostatectomy, brachytherapy, radiotherapy, cryotherapy and HIFU. Robotic partial nephrectomy and cryotherapy have changed the face of renal cancer. En-bloc resection of bladder cancer is challenging the traditional management of non-muscle invasive bladder cancer and becoming commonplace, while robotic cystectomy is also gaining popularity for muscle invasive bladder cancer. Newer surgical intervention related to BPE includes laser (holmium, thulium and green light), water-based treatment (Rezum, Aquablation) and other minimally invasive procedures such as prostate artery embolisation (PAE) and Urolift. Endourological procedures have incorporated newer laser types and settings such as moses technology, disposable ureteroscopes (URS) and minimisation of percutaneous nephrolithotomy (PCNL) instruments. All these technological innovations and improvements have led to shorter hospital stay, reduced cost, potential reduction in complications and improvement in the quality of life (QoL).

partial nephrectomy --- single site surgery --- sutureless --- CEUS --- contrast-enhanced ultrasound --- renal ultrasound --- image quality --- small renal mass (3–5) --- kidney stones --- metabolic syndrome --- urolithiasis --- nephrolithiasis --- kidney calculi --- diabetes mellitus --- acute kidney injury --- percutaneous nephrolithotomy --- urology --- artificial intelligence --- machine learning --- urinary incontinence --- kidney stone disease --- fertility --- reproductive urology --- renal cell carcinoma --- hydronephrosis --- urinary reflux --- endourology --- pediatric urology --- prostate cancer --- bladder cancer --- nephrostomy --- quality of life --- survival --- decision making --- ureteroscopy --- laser --- RIRS --- Moses --- holmium --- mineral water --- mineral composition --- drinking water --- still water --- sparkling water --- Ho:YAG laser --- thulium fiber laser --- laser fiber --- lithotripsy --- chronic prostatitis --- chronic pelvic pain syndrome --- extracorporeal shockwave therapy --- ESWT --- NIH-CPSI --- EHS --- IIEF-5 --- QoL --- urosepsis --- laser lithotripsy --- predictor factors --- PCNL --- renal tumour --- AI --- TFL

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Over the past decade, interest in plant biostimulants has been on the rise, compelled by the growing interest of researchers, extension specialists, private industries, and farmers in integrating these products in the array of environmentally friendly tools to secure improved crop performance, nutrient efficiency, product quality, and yield stability. Plant biostimulants include diverse organic and inorganic substances, natural compounds, and/or beneficial microorganisms such as humic acids, protein hydrolysates, seaweed and plant extracts, silicon, endophytic fungi like mycorrhizal fungi, and plant growth-promoting rhizobacteria belonging to the genera Azospirillum, Azotobacter, and Rhizobium. Other substances (e.g., chitosan and other biopolymers and inorganic compounds) can have biostimulant properties, but their classification within the group of biostimulants is still under consideration. Plant biostimulants are usually applied to high-value crops, mainly greenhouse crops, fruit trees and vines, open-field crops, flowers, and ornamentals to sustainably increase yield and product quality. The global biostimulant market is currently estimated at about $2.0 billion and is expected to reach $3.0 billion by 2021 at an annual growth rate of 13%. A growing interest in plant biostimulants from industries and scientists was demonstrated by the high number of published peer-reviewed articles, conferences, workshops, and symposia in the past ten years. This book compiles several original research articles, technology reports, methods, opinions, perspectives, and invited reviews and mini reviews dissecting the biostimulatory action of these natural compounds and substances and beneficial microorganisms on crops grown under optimal and suboptimal growing conditions (e.g., salinity, drought, nutrient deficiency and toxicity, heavy metal contaminations, waterlogging, and adverse soil pH conditions). Also included are contributions dealing with the effect as well as the molecular and physiological mechanisms of plant biostimulants on nutrient efficiency, product quality, and modulation of the microbial population both quantitatively and qualitatively. In addition, identification and understanding of the optimal method, time, rate of application and phenological stage for improving plant performance and resilience to stress as well as the best combinations of plant species/cultivar × environment × management practices are also reported. We strongly believe that high standard reflected in this compilation on the principles and practices of plant biostimulants will foster knowledge transfer among scientific communities, industries, and agronomists, and will enable a better understanding of the mode of action and application procedures of biostimulants in different cropping systems.

Crocus sativus L. --- biofertilization --- arbuscular mycorrhizal fungi --- antioxidant activity --- crocin --- picrocrocin --- polyphenols --- safranal --- Maize --- biostimulant --- root --- stress --- growth --- gene expression --- stem cuttings --- propagation --- root morphology traits --- indole-3-acetic acid (IAA) --- indole-3-butyric acid (IBA) --- gibberellins --- phenolic compounds --- nutrients --- nutraceutical potential --- soybean --- yield --- N organic fertilizer --- seaweed extract --- mycorrhizal inoculants --- phosphate-solubilizing microorganisms --- biofertilizers --- microorganism consortium --- biostimulants --- Crocus sativus --- Funneliformis mosseae --- glasshouse --- protected cultivation --- Rhizophagus intraradices --- substrate --- L-methionine --- L-tryptophan --- L-glycine --- lettuce --- nitrogen --- plant biostimulant --- environmental stress --- vegetables --- fruit quality --- plants biostimulants --- yielding --- Biostimulants --- Euglena gracilis --- algal polysaccharide --- β-glucan --- water stress --- tomato --- aeroponics --- Zea mays L --- lignohumate --- lignosulfonate --- biological activity --- nitrogen metabolism --- carbon metabolism --- proteins --- phenolics --- sugars --- Ascophyllum nodosum --- Solanum melongena --- heterostyly --- pollination efficiency --- soilless conditions --- abiotic stress --- alfalfa hydrolysate --- chitosan --- zinc --- ascorbic acid --- Fragaria x ananassa --- functional quality --- lycopene --- organic farming --- protein hydrolysate --- Solanum lycopersicum L. --- tropical plant extract --- fertilizer --- melatonin --- phytomelatonin --- plant protector --- plant stress --- Lactuca sativa L. --- legume-derived protein hydrolysate --- nitrate --- Septoria --- wheat --- Paraburkholderia phytofirmans --- thyme essential oil --- isotope --- phytoparasitic nematodes --- suppressiveness --- sustainable management --- anti-nutritional substances --- fat --- fibre --- morphotype --- protein --- corn --- imaging --- industrial crops --- maize --- next generation sequencing --- phenomics --- plant phenotyping --- row crops --- Bacillus subtilis --- carotenoids --- probiotics --- PGPR --- Mentha longifolia --- humic acid --- antioxidants --- arbuscular mycorrhizal symbiosis --- mycorrhizosphere --- AMF associated bacteria --- plant growth-promoting bacteria --- phosphate-solubilizing bacteria --- siderophore production --- soil enzymatic activity --- biological index fertility --- nitrogenase activity --- microelements fertilization (Ti, Si, B, Mo, Zn) --- seed coating --- cover crop --- vermicompost --- growth enhancement --- AM fungi --- PGPB --- water deficit --- common bean --- Glomus spp. --- organic acids --- pod quality --- seaweed extracts --- seed quality --- tocopherols --- total sugars --- bean --- amino acids --- phenols --- flavonoids --- microbial biostimulant --- non-microbial biostimulant --- Lactuca sativa L. var. longifolia --- mineral profile --- physiological mechanism --- photosynthesis --- biocontrol --- plant growth promotion --- soil inoculant --- Trichoderma --- Azotobacter --- Streptomyces --- deproteinized leaf juice --- fermentation --- lactic acid bacteria --- plant nutrition --- antioxidant capacity --- ornamental plants --- N fertilization --- nitrogen use efficiency --- leaf quality --- Spinacia oleracea L. --- sustainable agriculture --- Valerianella locusta L. --- isotopic labeling --- turfgrass --- humic acids --- leaf area index (LAI) --- specific leaf area (SLA) --- Soil Plant Analysis Development (SPAD) index --- tuber yield --- ultrasound-assisted water --- foliar spray --- Pterocladia capillacea --- bio-fertilizer --- growth parameters --- Jew’s Mallow --- CROPWAT model --- eco-friendly practices --- total ascorbic acid --- Mater-Bi® --- mineral composition --- SPAD index --- Bacillus thuringiensis --- Capsicum annuum --- microbiome --- strain-specific primer --- tracking --- sweet basil --- alfalfa brown juice --- biostimulation --- chlorophyll pigments --- histological changes --- humic substances --- protein hydrolysates --- silicon --- arbuscular mycorrhiza --- plant growth promoting rhizobacteria --- macroalgae --- microalgae --- abiotic stresses --- nutrient use efficiency --- physiological mechanisms