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The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclatur

HLA histocompatibility antigens --- Histocompatibility antigens. --- Isoantigens --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Major histocompatibility complex

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HLA histocompatibility antigens. --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Major histocompatibility complex

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The processing and presentation of antigens by major histocompatibility complex (MHC) molecules is a crucial immunological phenomenon in infectious disease, malignancy, autoimmune disease, and transplantation. In Antigen Processing and Presentation Protocols, well-recognized and innovative experimentalists detail their cutting-edge methods for studying this complex process. Drawing on expertise from biochemistry, cell biology, and immunology, they describe step-by-step methods designed to question how MHC-binding peptides are generated, to test how peptides are delivered to MHC molecules, to analyze MHC peptide-binding patterns, and to assay the T cell response to the MHC/peptide complex. Each method is presented in sufficient detail to be readily reproducible and includes notes about potential pitfalls and tips on how to avoid failures. Emphasis is given those technical steps critical for experimental success that are often omitted from methods published in the primary literature. Eminently accessible and state-of-the-art, Antigen Processing and Presentation Protocols provides both new and experienced investigators with highly practical tools that will extend the questions that can be asked, and effectively be answered, concerning antigen processing/presentation.

Molecular biology --- Antigen presenting cells --- Antigens --- HLA histocompatibility antigens --- Major histocompatibility complex --- Molecular immunology --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Immunity --- Immunoglobulins --- Immune system --- Immunology --- Accessory cells --- Immunologic accessory cells --- Immunocompetent cells --- Histocompatibility complex --- MHC (Immunogenetics) --- Immunogenetics --- Molecular aspects --- Immunology. --- Immunobiology --- Life sciences --- Serology

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Immunology --- Immune response --- HLA histocompatibility antigens --- Allergy and Immunology --- Histocompatibility Testing --- Regulation --- Immunologie --- Réaction immunitaire --- Antigènes HLA --- HLA histocompatibility antigens. --- Immunology. --- Allergy and Immunology. --- Périodiques. --- Régulation --- Regulation. --- Allergy Specialty --- Allergy, Immunology --- Immunology and Allergy --- Immunology, Allergy --- Specialty, Allergy --- Immunobiology --- Immune modulation --- Immunity --- Immunomodulation --- Immunoregulation --- Regulation of immunity --- Regulation of the immune response --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility --- Immunocompatibility --- Tissue Compatibility --- Compatibilities, Tissue --- Compatibility, Tissue --- Histocompatibilities --- Immunocompatibilities --- Tissue Compatibilities --- Life sciences --- Serology --- Idiotypic networks --- Biological response modifiers --- Ir genes --- Histocompatibility antigens --- Major histocompatibility complex --- Histocompatibility. --- Histocompatibilité. --- Periodicals. --- Tissue compatibility --- Immunological tolerance --- Transplantation immunology --- HLA Incompatibility --- Histoincompatibility --- Human Leukocyte Antigen Incompatibility --- HLA Incompatibilities --- Histoincompatibilities --- Incompatibility, HLA

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Immunodiagnosis --- Allergy and Immunology. --- HLA-D Antigens. --- Immunologic Techniques. --- Immunologic Tests. --- Receptors, Immunologic. --- Diagnostics immunologiques --- Immunodiagnosis. --- Immunological diagnosis --- Immunologic Receptor --- Immunological Receptors --- Immunologic Receptors --- Receptor, Immunologic --- Receptors, Immunological --- Diagnosis, Immunologic --- Immunologic Diagnosis --- Immunologic Test --- Immunological Tests --- Tests, Immunologic --- Diagnosis, Immunological --- Diagnoses, Immunologic --- Diagnoses, Immunological --- Immunodiagnoses --- Immunologic Diagnoses --- Immunological Diagnoses --- Immunological Diagnosis --- Immunological Test --- Test, Immunologic --- Test, Immunological --- Tests, Immunological --- Antibody Dissociation --- Immunologic Technic --- Immunologic Technics --- Immunologic Technique --- Immunological Technics --- Immunological Techniques --- Technic, Immunologic --- Technics, Immunologic --- Technique, Immunologic --- Techniques, Immunologic --- Antibody Dissociations --- Dissociation, Antibody --- Dissociations, Antibody --- Immunological Technic --- Immunological Technique --- Technic, Immunological --- Technics, Immunological --- Technique, Immunological --- Techniques, Immunological --- Allergy and Immunology --- HLA-D --- HLA-Dw --- Immune Response Associated Antigens, Human --- Antigens, HLA-D --- Class II Human Antigens --- HLA-Dw Antigens --- Human Class II Antigens --- Ia-Like Antigens, Human --- Immune Response-Associated Antigens, Human --- Immune-Associated Antigens, Human --- Immune-Response Antigens, Human --- Antigens, HLA D --- Antigens, HLA-Dw --- Antigens, Human Ia-Like --- Antigens, Human Immune-Associated --- Antigens, Human Immune-Response --- HLA D Antigens --- HLA Dw Antigens --- Human Ia-Like Antigens --- Human Immune-Associated Antigens --- Human Immune-Response Antigens --- Ia Like Antigens, Human --- Immune Associated Antigens, Human --- Immune Response Antigens, Human --- Allergy Specialty --- Allergy, Immunology --- Immunology and Allergy --- Immunology, Allergy --- Immunology --- Specialty, Allergy --- methods --- HLA-D Antigens --- Immunologic Techniques --- Immunologic Tests --- Receptors, Immunologic --- Immunity --- Immunochemistry --- Clinical immunology --- Diagnosis, Laboratory --- Immunoassay --- Journal --- Periodicals --- HLA-D Antigens.. --- HLA histocompatibility antigens. --- Antigènes HLA-D. --- Diagnostics immunologiques. --- HL-A histocompatibility antigens --- HLA antigens --- HLA transplantation antigens --- Human leukocyte antigens --- Transplantation antigens, Human --- Histocompatibility antigens --- Major histocompatibility complex