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This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions. In the second version, fourteen chapters will be updated base on the most recent research articles. Ten new chapters will be added.

Chemistry --- Histology. Cytology --- History of human medicine --- Human physiology --- celmembranen --- farmacologie --- fysiologie --- proteïnen --- Pharmacology. --- Proteins. --- Human physiology. --- Biological transport. --- Cell membranes. --- Protein Biochemistry. --- Human Physiology. --- Membrane Trafficking.

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This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 20 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions.

Chemical structure --- Biomembranes --- Histology. Cytology --- General biochemistry --- Human physiology --- Toxicology --- Pharmacology. Therapy --- celmembranen --- membranen (biologie) --- protein-engineering --- farmacologie --- biochemie --- biologie --- multimedia --- toxicologie --- fysiologie --- eiwitten --- moleculaire biologie --- Pharmacology. --- Proteins . --- Human physiology. --- Cell membranes . --- Pharmacology/Toxicology. --- Protein Science. --- Human Physiology. --- Membrane Biology.

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General biophysics --- General biochemistry --- Biomembranes --- Biochemistry --- Membranes (Biology) --- Biochimie --- Membranes (Biologie) --- Periodicals --- Périodiques --- Cell membranes --- Cell Membrane --- Membrane cellulaire --- #TS:KOME --- #ANTILTPNE9510 --- Life Sciences --- Chemistry --- General and Others --- Life Sciences. --- biochemie --- Périodiques --- EJBIOLO EJBIOMO EJMEDEC ELSEVIER-E EPUB-ALPHA-B EPUB-PER-FT MDBIOCHE MDBIOPHY --- Cytoplasmic Membrane --- Plasma Membrane --- Cell Membranes --- Cytoplasmic Membranes --- Membrane, Cell --- Membrane, Cytoplasmic --- Membrane, Plasma --- Membranes, Cell --- Membranes, Cytoplasmic --- Membranes, Plasma --- Plasma Membranes --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes --- Glycocalyces --- MDBIOCHE MDBIOPHY --- Periodicals. --- Cell Membrane.

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The fourth edition of this text highlights the authors' continuing commitment to provide molecular cell biology topics, supported by the experiments and techniques that established them.

CELLS --- Molecular biology --- Cells. --- Molecular Biology. --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Cell --- Cell Biology --- Basic Sciences. Molecular Biology --- Molecular Biology (General) --- Genetic Phenomena --- Molecular Biology (General). --- Cytologie --- Micro-organisme --- microorganisms --- Expérimentation en laboratoire --- Laboratory experimentation --- Membrane cellulaire --- cell membranes --- Technique immunologique --- Immunological techniques --- Cellenleer --- Moleculaire biologie --- Basic Sciences. Molecular Biology -- Molecular Biology (General) --- Cytology. --- Molecular biology. --- ALLW. --- moleculaire biologie --- Histology. Cytology --- cytologie --- Cytology --- Molecular Biology --- Cells --- Biochemistry --- Genetics --- Anatomy --- Biological Science Disciplines --- Biology --- Chemistry --- Natural Science Disciplines --- Disciplines and Occupations --- Health & Biological Sciences --- genetic engineering --- Biologie moléculaire --- celbiologie --- Biologie --- Basic Sciences. Molecular Biology -- Molecular Biology (General). --- Structure moleculaire --- CYTOLOGY --- MOLECULAR BIOLOGY --- GENOME --- CELL BIOLOGY --- MEMBRANES (BIOLOGICAL) --- TEXTBOOKS

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Nature Structural & Molecular Biology reflects the growing integration of structural and molecular studies. The journal places a strong emphasis on understanding the molecular mechanisms underlying biological processes. Specific areas include (but are not limited to) DNA replication, repair and recombination; chromatin structure and remodeling; transcription; translation; folding, processing, transport and degradation of proteins and RNA; signal transduction and membrane processes.

Molecular biology --- Genetics --- Molecular Biology --- Molecular Structure --- Cells --- Molecular structure --- Structural bioinformatics --- Biologie moléculaire --- Structure moléculaire --- Bio-informatique structurale --- methods --- ultrastructure --- Periodicals. --- Periodicals --- Périodiques --- Peri BUMP 6522 (M 2012) --- Molecular Structure. --- Cells. --- Molecular biology. --- methods. --- Molecular Biology. --- Structure, Molecular --- Molecular Structures --- Structures, Molecular --- Models, Molecular --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Genetic Phenomena --- ultrastructure. --- Life Sciences --- Cytology, Cell Biology --- Micro and Molecular Biology --- Biology --- Life Sciences. --- Micro and Molecular Biology. --- Biologie moléculaire --- Structure moléculaire --- Périodiques --- EBSCOASP-E EPUB-ALPHA-N EPUB-PER-FT --- Molecular biochemistry --- Molecular biophysics --- Cell --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cell Biology --- moleculaire biologie --- Life sciences --- Proteins --- Cell membranes --- Microscopy --- Life Sciences, general --- Biochemistry, general --- Protein Structure --- Membrane Biology --- Biological Microscopy --- Analysis, Microscopic --- Light microscopy --- Micrographic analysis --- Microscope and microscopy --- Microscopic analysis --- Optical microscopy --- Optics --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes (Biology) --- Glycocalyces --- Proteids --- Polypeptides --- Proteomics --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Biosciences --- Sciences, Life --- Science --- Composition