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Micro-Tomographic Atlas of the Mouse Skeleton Professor Itai Bab, Chief, Bone Laboratory, The Hebrew University of Jerusalem, Jerusalem, Israel Professor Ralph Müller, Director, Center for Bioengineering Research and Education, ETH Zürich, Switzerland Micro-Tomographic Atlas of the Mouse Skeleton serves as an essential guide containing unique systematic description of all calcified components of the mouse. This detailed atlas fulfils an emerging need for high resolution anatomical details as mice become a standard laboratory animal in skeletal research and the use of m CT technology is rapidly increasing as a key analytical tool in the study of bone. Key Features: Includes over 200 high resolution, two- and three dimensional m CT images of the exterior and interiors of all bones and joints Offers the spatial relationship of individual bones within complex skeletal units (e.g., skull, thorax, pelvis, extremities). All images are accompanied by detailed explanatory text that highlights special features and newly reported structures. Available for the first time in the Atlas: Detailed information on the micro-anatomy of the murine skeleton essential for the design of experiments and interpretation of results Comparative analyses on m CT-based morphometric parameters at the whole bone, cortical and trabecular levels including: Age differences (4-40 weeks) Gender differences Differences between main mouse strains (C57Bl/6J, SJL, C3H) Micro-Tomographic Atlas of the Mouse Skeleton offers a practical, comprehensive desk reference for all scientists and students interested in skeletal biology.

Mice --- Skeleton --- Anatomy --- Tomography. --- House mice --- House mouse --- Mouse --- Mus musculus --- Rodents --- Osteology --- Bones --- Bone and Bones --- Tomography, X-Ray Computed --- radiography --- anatomy & histology --- Biomedical engineering. --- Zoology. --- Animal physiology. --- Human anatomy. --- Neurobiology. --- Developmental biology. --- Biomedical Engineering and Bioengineering. --- Animal Physiology. --- Anatomy. --- Developmental Biology. --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Neurosciences --- Anatomy, Human --- Human biology --- Medical sciences --- Human body --- Animal physiology --- Animals --- Natural history --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Physiology --- Radiography --- Anatomy & histology

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The advent of molecular techniques has shifted the focus of physiology from its traditional role as an integrative science concerned with the study of regulatory mechanisms leading to adaptation and homeostasis, to a field preoccupied with the problems and challenges inherent in those techniques. In Integrative Physiology in the Proteomics and Post-Genomics Age, internationally recognized researchers highlight the major questions and accomplishments of modern physiological research and demonstrate that modern molecular methods can well be incorporated and strengthen the original integrative perspectives of physiology set out by Claude Bernard's concept of the "milieu interieur." Among the critical issues discussed are the place of functional genomics in regulatory physiology, the role of model systems in integrative physiology, the function of neural circuits in behavior and consciousness, and the influence of external challenges to the whole body and the environment on genes. The question of integrative physiology in curriculum design for the health sciences is also discussed. Perceptive and timely, Integrative Physiology in the Proteomics and Post-Genomics Age bridges the gap between molecular biology and whole body function, establishing the future of physiology as an integrative science based on new molecular insights.

Genomics. --- Proteomics. --- Molecular Biology. --- Physiology, Experimental. --- Molecular biology. --- Physiologie expérimentale --- Génomique --- Protéomique --- Biologie moléculaire --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Molecular biology --- Proteins --- Genome research --- Genomes --- Molecular genetics --- Experimental physiology --- Research --- Physiology, Experimental --- Genomics --- Proteomics --- Science --- Genetics --- Biological Science Disciplines --- Natural Science Disciplines --- Biology --- Computational Biology --- Chemistry --- Disciplines and Occupations --- Physiology --- Molecular Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Medicine. --- Human physiology. --- Biomedicine. --- Human Physiology. --- Human biology --- Medical sciences --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians

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Incisional hernia surgery has witnessed an important progress over the last years, not only as far as the pathophysiological and etiopathogenetic aspects are concerned, but also from a technical point of view. Thanks to the recent findings on genetical disorders of the collagen, incisional hernia is today considered a true "disease of the abdominal wall". Surgeons need to be aware of all the different repairing techniques, in order to make an elective choice and to keep side effects and recidives under control. Today, on the basis of the most recent research on synthesis of collagen and collagenolysis, the treatment of the incisional hernia should not disregard the use of synthetic prostheses and of biomaterials, both in the routinal surgical practice and in the most complex clinical cases. Surgeons, surgical residents, and medical students will find this volume very useful in their daily practice.

Medicine & Public Health. --- Surgery. --- Abdominal Surgery. --- General Surgery. --- Anatomy. --- Anesthesiology. --- Medicine. --- Human anatomy. --- Abdomen --- Médecine --- Anatomie humaine --- Anesthésiologie --- Chirurgie --- Postoperative Complications. --- Surgical Procedures, Operative -- methods. --- Ventral hernia -- Surgery. --- Surgical Mesh --- Reoperation --- Hernia, Ventral --- Postoperative Complications --- Abdominal Muscles --- Surgical Procedures, Operative --- Pathologic Processes --- Surgical Equipment --- Hernia, Abdominal --- Muscle, Skeletal --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Muscles --- Hernia --- Equipment and Supplies --- Pathological Conditions, Signs and Symptoms --- Musculoskeletal System --- Diseases --- Pathological Conditions, Anatomical --- Anatomy --- Surgery - General and By Type --- Surgery & Anesthesiology --- Health & Biological Sciences --- Abdominal wall --- Surgery, Operative. --- Ventral hernia --- Operative surgery --- Surgery --- Surgical techniques --- Technique --- Abdominal surgery. --- Anaesthesiology --- Anatomy, Human --- Human biology --- Medical sciences --- Human body --- Abdominal surgery --- Laparotomy --- Surgery, Primitive --- Medicine

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Sepsis is a multi-factorial disease process and this volume provides comprehensive and in-depth reviews of both the basic science and more practical aspects of patient management. These include detailed information on the epidemiology and genetics of sepsis as well as the metabolic and cardiovascular responses to infection. Infectious disease, in relation to sepsis, is well covered including chapters on unusual/exotic infections, control of infection and the rational use of antibiotics. Haematological aspects of sepsis are also reviewed in detail. Further chapters focus on the currently controversial areas of clinical trial design in sepsis and protocol-driven care. A specific chapter, with illustrated cases, draws practical lessons and offers useful management "tips". The patient with sepsis provides a major challenge to the hospital acute team and septic shock is the commonest cause of admission to General Critical Care Units in the industrialised world. The incidence of sepsis is also increasing, in part due to the more complex patient case mix which is a feature of modern hospital practice. This volume is useful to both trainees in Critical Care and Anaesthesia as well as Infectious Disease and General Medical trainees. It also provides qualified practitioners in these fields with a comprehensive resource on sepsis-related topics.

Medicine & Public Health. --- Infectious Diseases. --- Health Promotion and Disease Prevention. --- Anatomy. --- Dermatology. --- Pneumology/Respiratory System. --- Medicine. --- Human anatomy. --- Emerging infectious diseases. --- Pneumology. --- Médecine --- Anatomie humaine --- Dermatologie --- Maladies infectieuses émergentes --- Bloodborne infections. --- Sepsis. --- Septicemia. --- Septicemia --- Infection --- Systemic Inflammatory Response Syndrome --- Inflammation --- Bacterial Infections and Mycoses --- Pathologic Processes --- Diseases --- Pathological Conditions, Signs and Symptoms --- Sepsis --- Law - Non-U.S. --- Medicine --- Health & Biological Sciences --- Law, Politics & Government --- Infectious Diseases --- Law - Africa, Asia, Pacific & Antarctica --- Blood-borne diseases --- Blood-borne infections --- Bloodborne diseases --- Bloodborne infection --- Blood poisoning --- Poisoning, Blood --- Septicaemia --- Health promotion. --- Infectious diseases. --- Respiratory organs --- Diseases. --- Respiratory diseases --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education --- Skin --- Anatomy, Human --- Anatomy --- Human biology --- Medical sciences --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Communicable diseases --- Blood --- Transmission --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Health Workforce --- Respiratory organs—Diseases.

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S. E. BAILEY Department of Human Evolution Max Planck Institute for Evolutionary Anthropology Deutscher Platz 6 D-04103 Leipzig, Germany and Center for the Study of Human Origins, Department of Anthropology, New York University, 25 Waverly Place New York, NY 10003, USA sbailey@nyu. edu J. -J. HUBLIN Department of Human Evolution Max Planck Institute for Evolutionary Anthropology Deutscher Platz 6 D-04103 Leipzig, Germany hublin@eva. mpg. de When faced with choosing a topic to as teeth represent, by far, the most abundant be the focus of the first symposium material documenting different species of in Human Evolution at the Max Planck extinct non-human primates and hominins. As Institute for Evolutionary Anthropology in such, much of what we know about non- Leipzig, a paleoanthropological perspective human primate and hominin evolution is based of dental anthropology was a natural choice. on teeth. Teeth make up a disproportionate number Teeth have been a focus of interest for of the fossils discovered. They represent physical anthropologists over many gen- strongly mineralized organs of compact shape, ations. Teeth provide a multitude of which allow better preservation in geological information about humans – including deposits and archaeological sites than any cultural treatment, pathology, morphological other part of the skeleton. As a result, variation, and development. The presence of since the discoveries of the first fossils of culturally induced wear (toothpick grooves, extinct species, vertebrate paleontology has for example) reveals something about what been built primarily on analyses of teeth.

beeldverwerking --- Computer. Automation --- Ethnology. Cultural anthropology --- stomatologie --- Human anatomy --- vormgeving --- Artificial intelligence. Robotics. Simulation. Graphics --- simulaties --- Stomatology --- anatomie --- Teeth --- Human evolution. --- Teeth, Fossil. --- Paleoanthropology. --- Evolution (Biology). --- Dental anthropology. --- Animals. --- Humans. --- Fossils. --- Paleodontology. --- Paleodontology --- Tooth --- Tooth Wear. --- Anatomy, Comparative. --- Evolution. --- Primates. --- Hominidae. --- Biological Evolution. --- SOCIAL SCIENCE --- Methods. --- Anatomy & histology. --- Anthropology --- Physical. --- Anthropology. --- Life sciences. --- Paleontology . --- Human anatomy. --- Life Sciences, general. --- Evolutionary Biology. --- Paleontology. --- Anatomy. --- Evolutionary biology. --- Anatomy, Human --- Anatomy --- Human biology --- Medical sciences --- Human body --- Fossilogy --- Fossilology --- Palaeontology --- Paleontology, Zoological --- Paleozoology --- Historical geology --- Zoology --- Fossils --- Prehistoric animals in motion pictures --- Biosciences --- Sciences, Life --- Science --- Human beings --- Animal evolution --- Animals --- Biological evolution --- Darwinism --- Evolutionary biology --- Evolutionary science --- Origin of species --- Biology --- Evolution --- Biological fitness --- Homoplasy --- Natural selection --- Phylogeny --- Primitive societies --- Social sciences --- Dental anthropology --- Evolution (Biology) --- Human evolution --- Paleoanthropology --- Teeth, Fossil